153775-33-8Relevant articles and documents
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
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Page/Page column 56; 60, (2013/11/05)
The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as m PGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (m PGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.
CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS
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Page/Page column 21, (2009/07/17)
The present invention relates to compounds useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acq
CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS
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Page/Page column 11, (2009/06/27)
The present invention relates to compounds useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).