1538556-41-0

Basic information

• Product Name: DL-[¹³C₆]-4-methoxyamphetamine hydrochloride
• Synonyms: DL-[¹³C₆]-4-methoxyamphetamine hydrochloride
• CAS NO: 1538556-41-0
• Molecular Weight: 207.63
• Mol File: 1538556-41-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: DL-[¹³C₆]-4-methoxyamphetamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: DL-[¹³C₆]-4-methoxyamphetamine hydrochloride(1538556-41-0)
• EPA Substance Registry System: DL-[¹³C₆]-4-methoxyamphetamine hydrochloride(1538556-41-0)

Safety Data

• Hazardous Substances Data: 1538556-41-0(Hazardous Substances Data)

Upstream product

• 1538556-43-2 [¹³C₆]-4-methoxyphenyl-2-propanone 
• 89059-34-7 [¹³C₆]phenol 
• 152571-52-3 anisole-1,2,3,4,5,6-¹³C₆ 

Relevant articles and documents

Synthesis of [13C6]-labelled phenethylamine derivatives for drug quantification in biological samples

The availability of high-quality 13C-labelled internal standards will improve accurate quantification of narcotics and drugs in biological samples. Thus, the synthesis of 10 [13C6]-labelled phenethylamine derivatives, namely amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 3,4-methylenedioxymethamphetamine, 3,4-methylenedioxy-N-ethylamphetamine, 4-methoxyamphetamine, 4-methoxymethamphetamine, 3,5-dimethoxyphenethylamine 4-bromo-2,5- dimethoxyphenethylamine and 2,5-dimethoxy-4-iodophenethylamine, have been undertaken. [13C6]-Phenol proved to be an excellent starting material for making 13C-labelled narcotic substances in the phenethylamine class, and a developed Stille-type coupling enabled an efficient synthesis of the 3,4-methylenedioxy and 4-methoxy derivatives. The pros and cons of alternative routes and transformations are also discussed. The [ 13C6]-labelled compounds are intended for use as internal standards in forensic analysis, health sciences and metabolomics studies by gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry. Copyright