15386-99-9

Usage

Appearance

White to light yellow solid

Solubility

Slightly soluble in water, soluble in organic solvents

Uses

a. Precursor in the synthesis of pharmaceuticals
b. Precursor in the synthesis of agrochemicals
c. Precursor in the synthesis of dyes
d. Reagent in laboratory research
e. Preparation of heterocyclic compounds

Toxicity

Potential toxic effects, should be handled with care in a controlled laboratory environment

InChI:InChI=1/C10H8ClNO2/c11-7-2-1-3-8(6-7)12-9(13)4-5-10(12)14/h1-3,6H,4-5H2

Upstream product

• 15386-96-6 3-(3-Chlor-phenylcarbamoyl)-propionsaeure 
• 108-42-9 3-chloro-aniline 

Downstream Products

• 34281-49-7 3,4-dichloro-1-(3-chlorophenyl)-1H-pyrrole-2,5-dione 

Relevant academic research and scientific papers

Synthesis of 3-(5-amino-1: H -1,2,4-triazol-3-yl)propanamides and their tautomerism

Two complementary pathways for the preparation of N-substituted 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides (5) were proposed and successfully realized in the synthesis of 20 representative examples. These methods use the same types of starting material

Radical-mediated dehydrative preparation of cyclic imides using (NH4)2S2O8-DMSO: Application to the synthesis of vernakalant

Ammonium persulfate-dimethyl sulfoxide (APS-DMSO) has been developed as an efficient and new dehydrating reagent for a convenient one-pot process for the synthesis of miscellaneous cyclic imides in high yields starting from readily available primary amines and cyclic anhydrides. A plausible radical mechanism involving DMSO has been proposed. The application of this facile one-pot imide forming process has been demonstrated for a practical synthesis of vernakalant.

Substituent chemical shifts of N-arylsuccinanilic acids, N-arylsuccinimides, N-arylmaleanilic acids, and N-arylmaleimides

NMR spectra of a series of N-arylsuccinanilic acids, N-arylsuccinimides, N-arylmaleanilic acids, and N-arylmaleimides were examined to estimate the electronic effect of the amide and imide groups on the chemical shifts of the hydrogen and carbon nuclei of the benzene ring.