153864-55-2

Upstream product

• 98760-08-8 (1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester 
• 108-98-5 thiophenol 
• 149451-80-9 (2S,3S)-3-(t-butoxycarbonylamino)-4-phenylbutane-1,2-diol 
• 116949-67-8 (2S,3S)-2-azido-1-phenyl-butane-3,4-diol 
• 78571-81-0 (R,R)-3-(phenylmethyl)oxiranemethanol 
• 42238-15-3 (2E)-4-phenylbut-2-en-1-ol 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 799560-21-7 (2S,3S)-3-(tert-butoxycarbonylamino)-4-phenyl-1-phenylsulfonyl-2-butanol 
• 799560-42-2 (3S,E)-3-(tert-butoxycarbonylamino)-4-phenyl-1-phenylsulfonyl-1-butene 

Relevant academic research and scientific papers

Enantiodivergent, catalytic asymmetric synthesis of γ-amino vinyl sulfones

A set of diversely substituted N-Boc-γ-amino vinyl sulfones has been prepared by a four-step procedure from readily available, highly enantiopure anti-N-Boc-3-amino-1,2-alkanediols. This new route, which does not depend on the accessibility of α-amino acids as starting materials, is noteworthy for its efficiency, for its generality, and for the fact that both enantiomers of a given γ-amino vinyl sulfone can be obtained with equal ease.

Diastereoselective epoxidation of dipeptide olefins

m-Chloroperbenzoic acid (MCPBA) epoxidation of dipeptide olefins proceeds in high syndiastereoselectivity (38:1-300:1). This is partially caused by conformational constants introduce by the side chain that orients the allylic NH in a favorable position for hydrogen bonding to MCPBA. The possibility of an additional hydrogen bond between the N-terminal NH and MCPBA is excluded.