153886-90-9Relevant academic research and scientific papers
Mitochondrial targeting of selective electron scavengers: Synthesis and biological analysis of hemigramicidin-TEMPO conjugates
Wipf, Peter,Xiao, Jingbo,Jiang, Jianfei,Belikova, Natalia A.,Tyurin, Vladimir A.,Fink, Mitchell P.,Kagan, Valerian E.
, p. 12460 - 12461 (2005)
Synthetic hemigramicidin S-peptidyl TEMPO conjugates are effectively delivered into cells and mitochondria, where they act as electron scavengers and exert protection against apoptosis. Our delivery approach is based on the use of specific structural sign
TARGETED NITROXIDE AGENTS
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Page/Page column 22; 28-29, (2010/03/02)
Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cro
FACILE SYNTHESIS OF GRAMICIDIN S VIA CYCLIZATION OF A LINEAR PENTAPEPTIDE
Minematsu, Joshihiro,Waki, Michinori,Suwa, Kazushi,Kato, Tetsuo,Izumiya, Nobuo
, p. 2179 - 2180 (2007/10/02)
Azide and N-hydroxysuccinimide ester of five pentapeptides related to gramicidin S (cyclic decapeptide) were cyclized to determine the ratio of dimer to monomer in the cyclization product, the pentapeptide dervative with D-Phe as C-terminus giving the dimer in good yield.
