1539-39-5

Basic information

• Product Name: Gapicomine
• Synonyms: Gapicomine;1-(4-pyridinyl)-N-(4-pyridinylmethyl)methanamine(SALTDATA: HCl);1-(4-pyridinyl)-N-(4-pyridinylmethyl)methanamine 1HCl;1-(4-pyridinyl)-N-(4-pyridinylMethyl)MethanaMine hydrochloride (SALTDATA: HCl)
• CAS NO: 1539-39-5
• Molecular Formula: C₁₂H₁₃N₃
• Molecular Weight: 199.256
• Mol File: 1539-39-5.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 359.2°Cat760mmHg
• Flash Point: 171°C
• Appearance: /
• Density: 1.118g/cm³
• Vapor Pressure: 2.41E-05mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 5.80±0.20(Predicted)
• CAS DataBase Reference: Gapicomine(CAS DataBase Reference)
• NIST Chemistry Reference: Gapicomine(1539-39-5)
• EPA Substance Registry System: Gapicomine(1539-39-5)

Safety Data

• Hazardous Substances Data: 1539-39-5(Hazardous Substances Data)

Usage

General Description

Gapicomine is a chemical compound that belongs to the class of amines and is known for its potential use as an antibiotic. It is believed to have antimicrobial properties and has been studied for its efficacy against various pathogenic bacteria. Gapicomine has also been investigated for its potential as an agricultural fungicide. Research has shown that this compound may have promising biological activity and has the potential to be developed into a therapeutic agent for the treatment of bacterial infections. However, further studies are needed to fully understand its mechanism of action and its potential application in medicine and agriculture.

InChI:InChI=1/C12H13N3/c1-5-13-6-2-11(1)9-15-10-12-3-7-14-8-4-12/h1-8,15H,9-10H2

Upstream product

• 3731-53-1 4-(aminomethyl)pyridine 
• 2038-57-5 3-Phenylpropan-1-amine 
• 696-54-8 pyridine-4-aldoxime 
• 872-85-5 pyridine-4-carbaldehyde 
• 1822-51-1 4-picolylchloride hydrochloride 
• 100-48-1 pyridine-4-carbonitrile 
• 110-58-7 n-Pentylamine 

Relevant articles and documents

On-line reaction monitoring and mechanistic studies by mass spectrometry: Negishi cross-coupling, hydrogenolysis, and reductive amination

Reaction monitoring using inductive ESI mass spectrometry allows chemical reactions to be tracked in real time, including air- and moisture-sensitive as well as heterogeneous reactions. Highly concentrated solutions can also be monitored for long periods without emitter clogging. Sheath gas assists in nebulization and a sample splitter reduces the delay time and minimizes contamination of the instrument. Short-lived intermediates (ca. 5 s) were observed in Pd/C-catalyzed hydrogenolysis, and several intermediates were seen in Negishi cross-coupling reactions. Fast and simple: A reaction monitoring system based on inductive ESI mass spectrometry provides a fast and simple way to monitor chemical reactions, including air-/moisture-sensitive reactions, continuously. It also provides information on solution-phase organic reaction mechanisms as shown by the observation of short-lived intermediates in Pd/C-catalyzed hydrogenolysis and several intermediates in Negishi cross-coupling reactions.

Cobalt complex, preparation method thereof, and application thereof in selective catalysis of transfer hydrogenation reaction of cyano group

The invention discloses a cobalt complex, a preparation method thereof, and an application thereof in the selective catalysis of a transfer hydrogenation reaction of a cyano group. The structural formula of the cobalt complex is represented by formula I. The cobalt complex is prepared through a reaction of a cobalt salt and an NNP ligand or a PNP ligand under the protection of an inert atmosphere;and the chemical formula of the cobalt salt is CoX12, wherein X1 represents halogen, a sulfate radical, a perchlorate radical, a hexafluorophosphate radical, a hexafluoroantimonate radical, a tetrafluoroborate radical, a trifluoromethanesulfonate radical or a tetra(pentafluorophenyl)borate radical. The cobalt complex can be used in the selective catalysis of the transfer hydrogenation reaction ofthe cyano group to obtain a primary amine compound, a secondary amine compound and a tertiary amine compound, the primary amine compound, the secondary amine compound and the tertiary amine compoundare important intermediates in a series of subsequent functionalizing reactions, and the cobalt complex has a very high catalysis activity, and has great research values and a great application prospect.

Nano-sized La0.5Ca0.5CoO3-mediated reduction by nabh4 of aryl nitriles to bis-(benzyl) amines

Nano-sized La0.5Ca0.5CoO3 perovskite, which was produced via the sol-gel method, was an efficient heterogeneous catalyst in combination with NaBH4 for the rapid chemoselective reduction of aryl nitriles to bis-(benzyl)amines at 40°C in good to excellent yields. The physico-chemical properties of the catalyst were characterized by means of differential thermal analysis (DTA), thermogravimetric analysis (TGA), X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDX) and particle size distributions images. The results show that nanoparticles have regular shapes with well-defined crystal faces with an average size of 30 nm.