153901-75-8Relevant articles and documents
Synthesis of 4-amino/hydroxy-6-methylthio-1/2-(2',2'-diethoxyethyl)-1H/2H-pyrazolo[ 3,4-d]pyrimidines and their antiallergic activity
Avasthi,Garg,Chandra,Bhakuni,Gupta,Srimal
, p. 585 - 591 (2007/10/02)
The synthesis of a series of 4-amino/hydroxy-6-substituted-1/2-(2',2'-diethoxyethyl)-1H/2H-pyrazolo [3,4-d]pyrimidines by alkylation of substituted pyrazolo[3,4-d]pyrimidines has been described, and their antiallergic activity evaluated in mice. The 2 most active compounds 4b and 5b were also tested in the rat. The most active compound 4b showed non-significant antihistaminic or antiserotoninergic activity.