6288-89-7

Basic information

• Product Name: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine
• Synonyms: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine
• CAS NO: 6288-89-7
• Molecular Formula: C₇H₈N₄S₂
• Molecular Weight: 212.29522
• Mol File: 6288-89-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 482.6°C at 760 mmHg
• Flash Point: 245.6°C
• Appearance: /
• Density: 1.48g/cm³
• Vapor Pressure: 5.3E-09mmHg at 25°C
• Refractive Index: 1.727
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine(6288-89-7)
• EPA Substance Registry System: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine(6288-89-7)

Safety Data

• Hazardous Substances Data: 6288-89-7(Hazardous Substances Data)

Usage

Description

4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine is a heterocyclic compound belonging to the pyrazolo[3,4-d]pyrimidine family, characterized by the presence of two methylthio groups at the 4th and 6th positions of the pyrazolo[3,4-d]pyrimidine ring. 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine possesses potential pharmacological properties and has been a subject of interest in medicinal chemistry for its diverse applications.

Uses

Used in Pharmaceutical Development:
4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine is used as a key component in the development of novel pharmaceuticals due to its antiproliferative and antitumor activities. Its potential in medicinal chemistry makes it a promising candidate for creating new drugs to combat various types of cancer.
Used in Antiviral Applications:
In the field of antiviral research, 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine is used as a potential antiviral agent against certain strains of viruses. Its effectiveness in inhibiting viral replication and reducing viral load makes it a valuable compound for further study and development.
Used in Anti-inflammatory Applications:
4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine is utilized as an anti-inflammatory agent in preclinical studies. Its ability to reduce inflammation and alleviate symptoms associated with inflammatory conditions positions it as a potential therapeutic option for various inflammatory diseases.
Used in Antioxidant Applications:
As an antioxidant agent, 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine is used to combat oxidative stress and protect cells from damage caused by reactive oxygen species. Its potential in this area highlights its versatility and importance in the field of medicinal chemistry for the development of treatments aimed at preventing or treating oxidative stress-related disorders.

InChI:InChI=1/C7H8N4S2/c1-12-6-4-3-8-11-5(4)9-7(10-6)13-2/h3H,1-2H3,(H,8,9,10,11)

Upstream product

• 42754-96-1 4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine 
• 100047-41-4 4-methylsulfanyl-1,7-dihydro-pyrazolo[3,4-d]pyrimidin-6-one 
• 7508-59-0 6-chloro-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-thione 
• 5334-33-8 4,5-Dihydro-4-thioxo-1H-pyrazolo[3,4-d]pyrimidin-6(7H)-one 
• 2465-59-0 oxypurinol 
• 5334-32-7 1H-pyrazolo[3,4-d]pyrimidin-4,6-dithione 
• 74-88-4 methyl iodide 
• 74-93-1 methylthiol 
• 5334-32-7 1⁽²⁾,7-dihydro-pyrazolo[3,4-d]pyrimidine-4,6-dithione 
• 6288-85-3 6-chloro-4-methylsulfanyl-1⁽²⁾H-pyrazolo[3,4-d]pyrimidine 

Downstream Products

• 1058209-06-5 C₂₀H₂₂N₄O₅S₂ 
• 124684-80-6 6-Methylthio-4(5H)-oxo-1-β-(2,3,5-tri-O-benzyl-D-arabinofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 124684-82-8 6-Amino-4(5H)-oxo-1-β-(2,3,5-tri-O-benzyl-D-arabinofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 112722-67-5 [2-(3,4-Dimethoxy-phenyl)-ethyl]-[6-methanesulfonyl-1-(tetrahydro-furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-amine 
• 112697-30-0 6-Methanesulfonyl-4-(4-phenyl-piperazin-1-yl)-1-(tetrahydro-furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 112697-28-6 [6-Methanesulfonyl-1-(tetrahydro-furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-(2-p-tolyl-ethyl)-amine 
• 115538-43-7 6-Methylsulfanyl-4-(4-phenyl-piperazin-1-yl)-1-(tetrahydro-pyran-2-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 115523-25-6 [6-Methanesulfonyl-1-(tetrahydro-pyran-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-phenethyl-amine 
• 112697-24-2 [2-(3,4-Dimethoxy-phenyl)-ethyl]-[6-methylsulfanyl-1-(tetrahydro-furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-amine 
• 112697-39-9 [2-(3,4-Dimethoxy-phenyl)-ethyl]-[6-methoxy-1-(tetrahydro-furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-amine 
• 112697-22-0 6-Methylsulfanyl-4-(4-phenyl-piperazin-1-yl)-1-(tetrahydro-furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 112697-37-7 6-Methoxy-4-(4-phenyl-piperazin-1-yl)-1-(tetrahydro-furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 112697-35-5 [6-Methoxy-1-(tetrahydro-furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-(2-p-tolyl-ethyl)-amine 
• 112697-20-8 [6-Methylsulfanyl-1-(tetrahydro-furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-(2-p-tolyl-ethyl)-amine 

Relevant articles and documents

Synthesis and antiviral activity of some C2-, C4-, and C6-substituted pyrazolo[3,4-d]pyrimidine acyclonucleosides with the alkylating chains of ACV, HBG, and iso-DHPG

A useful route to obtain trisubstituted pyrazolo[3,4-d]pyrimidines 14-17 is described. Those later were coupled with the alkylating agents 18-20 as in ACV, HBG, and iso-DHPG to give, after deprotection, the desired acylonucleosides 33-44 . Almost all of t