15398-00-2

Basic information

• Product Name: 1H-Pyrrole, 2,4-bis(4-methylphenyl)-
• Synonyms: 2,4-bis(4-methylphenyl)pyrrole;1H-Pyrrole,2,4-bis(4-methylphenyl)
• CAS NO: 15398-00-2
• Molecular Formula: C18H17N
• Molecular Weight: 247.34
• Mol File: 15398-00-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 214-216 °C
• Boiling Point: 433.9±24.0 °C(Predicted)
• Density: 1.071±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Pyrrole, 2,4-bis(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 2,4-bis(4-methylphenyl)-(15398-00-2)
• EPA Substance Registry System: 1H-Pyrrole, 2,4-bis(4-methylphenyl)-(15398-00-2)

Safety Data

• Hazardous Substances Data: 15398-00-2(Hazardous Substances Data)

Usage

Structure

A five-membered aromatic ring with one nitrogen atom and two 4-methylphenyl groups attached to positions 2 and 4 of the pyrrole ring.

Type of compound

Pyrrole derivative, which is a heterocyclic aromatic compound.

Usage

Mainly used in research and development, as well as a building block in the synthesis of pharmaceuticals and agrochemicals.

Hazard classification

Classified as a hazardous substance.

Health hazards

Can cause irritation to the skin, eyes, and respiratory system upon exposure.

Safety precautions

Proper handling and safety precautions should be taken when working with this chemical.

Upstream product

• 97691-66-2 1,3-bis(4-methylphenyl)prop-2-yn-1-one 
• 152801-73-5 2-bromo-1-p-tolylethanone O-methyl oxime 
• 6595-30-8 2-azido-1-(4-methylphenyl)ethan-1-one 
• 32687-33-5 3-p-tolyl-2H-azirine 

Relevant articles and documents

SmI2-mediated synthesis of 2,4-diarylpyrroles from phenacyl azides

A novel reduction of phenacyl azides induced by SmI2 was investigated and 2,4-diarylpyrroles were prepared in moderate to good yields under mild conditions.

Ytterbium-mediated synthesis of 2,4-diarylpyrroles from α-bromo oxime ethers

A novel and efficient ytterbium promoted reductive cyclisation dimerization of α-bromo-oxime ethers affording 2,4-diarylpyrroles with high regioselectivity has been developed. Compared with the reported synthesis methods, the method has the following advantages: readily available and safe starting material, one-pot single step operation and mild and neutral reaction conditions.

SmI2-mediated reduction of phenacyl azides: A novel preparation of 2,4-diarylpyrroles

A novel reductive cyclisation of phenacyl azides brought about by samarium iodide is described in this paper. By this process several 2,4-diarylpyrroles have been prepared.