153994-67-3

Usage

Uses

Used in Pharmaceutical Industry:
3-(1-Aminoethyl)benzonitrile is used as a synthetic intermediate for the development of various pharmaceuticals, contributing to the creation of new drugs and enhancing the therapeutic options available for treating different health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 3-(1-Aminoethyl)benzonitrile serves as a crucial intermediate in the synthesis of agrochemicals, playing a significant role in the production of pesticides and other compounds that protect crops and enhance agricultural productivity.
Used in Dye Manufacturing:
3-(1-Aminoethyl)benzonitrile is utilized as an intermediate in the manufacture of dyes, contributing to the coloration and quality of various products in the textile, paint, and plastics industries.
Used in Organic Compounds Synthesis:
3-(1-Aminoethyl)benzonitrile is also employed in the synthesis of other organic compounds, broadening its applications across multiple chemical and industrial processes, and highlighting its versatility in chemical research and development.

Upstream product

• 6136-68-1 3-acethylbenzonitrile 
• 24964-64-5 3-Cyanobenzaldehyde 

Downstream Products

• 127852-22-6 (S)-α-(m-cyanophenyl)ethylamine 
• 127852-31-7 (R)-α-(m-cyanophenyl)ethylamine 
• 127733-50-0 3-((S)-1-{[1-(2-Hydroxy-phenyl)-meth-(E)-ylidene]-amino}-ethyl)-benzonitrile 
• 1191908-02-7 5-chloro-1-(1-(3-cyanophenyl)ethyl)-2-imino-1,2-dihydropyridine-3-carboxamide monohydrochloride 
• 6136-68-1 3-acethylbenzonitrile 

Relevant academic research and scientific papers

ERK INHIBITORS AND USES THEREOF

The present disclosure provides compounds and compositions that are inhibitors of ERK1, ERK2, or both, and methods of use thereof.

Substituted pteridines for the treatment of inflammatory diseases

The invention relates to new pteridines which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers, as

Optically active amines. 34.1 Application of the benzene chirality rule to ring-substituted phenylcarbinamines and carbinols

The negative sign of the 1Lb, Cotton effects (CEs) from about 250 to 270 nm in the circular dichroism (CD) spectra of (R)-α-phenylethylamine and (R)-α-phenylethyl alcohol and other phenylalkylcarbinamines and carbinols is determined by vibronic borrowing from allowed transitions at shorter wavelength. On ring substitution, bond transition moments are induced in the benzene ring bonds adjacent to the attachment bond of the chiral group, resulting in enhanced coupling of the 1Lb transition with the chiral group. A sign reversal for the 1Lb, CEs on para substitution with an atom or group with a positive spectroscopic moment (C1, CH3) can be viewed as the overshadowing of the vibronic contribution by an induced contribution of opposite sign On para substitution with a group with a negative spectroscopic moment (CF3, CN), the sign of the 1Lb CEs is unchanged since the vibronic and induced contributions have the same sign. Meta substitution by an atom or group will result in bond moments in an opposite sense from that caused by the same atom or group in the para position. Thus on meta substitution by a group with a positive spectroscopic moment (C1, CH3), both the vibronic and induced contributions have the same sign, and the sign of the 1Lb CEs is the same as that of the unsubstituted parent. For meta substitution by a group with a negative spectroscopic moment (CF3, CN), the sign of the induced contribution is opposite to that of the vibronic contribution. In the case of CF3 and CN groups, the latter is more important than the former, and the sign of the 1Lb CEs is the same as that of the unsubstituted parent. Ortho substitution again reverses the sense of the induced bond transition moments from that induced by the same meta substituents. Thus, provided the position of the substituent and its spectroscopic moment are taken into account the absolute configuration of substituted phenylmethylcarbinamines and carbinols can often be assigned.