154052-44-5Relevant academic research and scientific papers
Inhibitory effects of multi-substituted benzylidenethiazolidine-2,4-diones on LDL oxidation
Jeong, Tae-Sook,Kim, Ju-Ryoung,Kim, Kyung Soon,Cho, Kyung-Hyun,Bae, Ki-Hwan,Lee, Woo Song
, p. 4017 - 4023 (2004)
Multi-substituted benzylidenethiazolidine-2,4-diones 3a-h were synthesized by Knoevenagel condensation of di- or tri-substituted 4-hydroxybenzaldehydes [or 1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethanone] 1 with thiazolidine-2,4-dione (2) and evaluated for
Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
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, (2008/06/13)
Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
Regiospecific reduction of 5-benzylidene-2,4-thiazolidinediones and 4- oxo-2-thiazolidinethiones using lithium borohydride in pyridine and tetrahydrofuran
Giles, Robert G.,Lewis, Norman J.,Quick, John K.,Sasse, Michael J.,Urquhart, Michael W. J.,Youssef, Latifa
, p. 4531 - 4537 (2007/10/03)
The novel regiospecific and general reduction of 5-benzylidene-2,4- thiazolidinediones and 5-benzylidene-4-oxo-2-thiazolidinethiones to the corresponding 5-benzyl derivatives has been accomplished using lithium borohydride in pyridine and tetrahydrofuran. Sodium borohydride and lithium chloride can also be used under these conditions, which represents a cheaper alternative to lithium borohydride. (C) 2000 Elsevier Science Ltd.
Synthesis and Biological Evaluation of 5-methylene>oxazoles, -thiazoles, and -imidazoles: Novel Dual 5-Lipoxygenase and Cyclooxygenase Inhibitors with Antiinflammatory Activity
Unangst, Paul C.,Connor, David T.,Cetenko, Wiaczeslaw A.,Sorenson, Roderick J.,Kostlan, Catherine R.,et al.
, p. 322 - 328 (2007/10/02)
A variety of benzylideneoxazoles, -thiazoles, and -imidazoles derived from 2,6-di-tert-butylphenol were prepared and evaluated as dual inhibitors of 5-lipoxygenase and cyclooxygenase in rat basophilic leukemia (RBL-1) cells.The target compounds exhibit va
