154052-49-0Relevant articles and documents
Synthesis and Biological Evaluation of 5-methylene>oxazoles, -thiazoles, and -imidazoles: Novel Dual 5-Lipoxygenase and Cyclooxygenase Inhibitors with Antiinflammatory Activity
Unangst, Paul C.,Connor, David T.,Cetenko, Wiaczeslaw A.,Sorenson, Roderick J.,Kostlan, Catherine R.,et al.
, p. 322 - 328 (2007/10/02)
A variety of benzylideneoxazoles, -thiazoles, and -imidazoles derived from 2,6-di-tert-butylphenol were prepared and evaluated as dual inhibitors of 5-lipoxygenase and cyclooxygenase in rat basophilic leukemia (RBL-1) cells.The target compounds exhibit va