154055-59-1

Basic information

• Product Name: 2-(3-hydroxypropylamino)-1-phenacylbenzimidazole hydrobromide
• Synonyms: 2-(3-hydroxypropylamino)-1-phenacylbenzimidazole hydrobromide
• CAS NO: 154055-59-1
• Molecular Weight: 390.28
• Mol File: 154055-59-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(3-hydroxypropylamino)-1-phenacylbenzimidazole hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-hydroxypropylamino)-1-phenacylbenzimidazole hydrobromide(154055-59-1)
• EPA Substance Registry System: 2-(3-hydroxypropylamino)-1-phenacylbenzimidazole hydrobromide(154055-59-1)

Safety Data

• Hazardous Substances Data: 154055-59-1(Hazardous Substances Data)

Upstream product

• 70-11-1 α-bromoacetophenone 
• 120161-08-2 3-[(1H-benzimidazol-2-yl)amino]propan-1-ol 

Downstream Products

• 416890-59-0 2-(3-hydroxypropylamino)-1-phenacylbenzimidazole 
• 174312-29-9 3-(2-phenyl-1H-imidazo[1,2-a]benzimidazol-1-yl)propan-1-ol 
• 154054-81-6 10-phenacyl-2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazole 
• 1228647-49-1 1-(3-bromopropyl)-2-phenylimidazo[1,2-a]benzimidazole hydrobromide 

Relevant articles and documents

Research in the field of imidazo[1,2-a]benzimidazole derivatives: XXVII. 1-acylmethyl-2-(ω-hydroxyalkylamino)-benzimidazoles and their transformation into derivatives of tricyclic systems

1-Acylmethyl-2-(ω-hydroxyalkylamino)benzimidazoles were synthesized and their behavior under various conditions was investigated: at the thermolysis without solvent, at heating in DMF or in 2-aminoethanol, hydrohalic acids, and acetic anhydride, in the presence of chlorinating agents (SOCl2, POCl3). Depending on the reaction conditions derivatives were obtained of 1H-imidazo[1,2-a]-benzimidazole, 9H-2,3-dihydroimidazo[1,2-a] benzimidazole, and 10H-2,3,4,10-tetrahydropyrimido[1,2-a]-benzimidazole that were suitable synthons for the synthesis of functionally substituted derivatives of these tricyclic systems.