120161-08-2

Usage

Derivative of propanol

As a derivative of propanol, it retains some properties of the parent compound, such as its solubility and ability to act as a solvent.

Benzimidazole group

The presence of the benzimidazole group in the compound contributes to its pharmacological properties and potential applications in the synthesis of pharmaceuticals and agrochemicals.

Potential applications in medicinal chemistry

Due to the unique structure and properties of 1-Propanol,3-(1H-benzimidazol-2-ylamino)-(9CI), it may have potential uses in the field of medicinal chemistry and drug development.

Need for further research

Further investigation and research are required to explore the potential uses and effects of 1-Propanol,3-(1H-benzimidazol-2-ylamino)-(9CI) in various applications.

Upstream product

• 4857-06-1 2-chloro-1H-benzoimidazole 
• 156-87-6 propan-1-ol-3-amine 
• 40828-54-4 1H-benzimidazole-2-sulfonic acid 

Downstream Products

• 154055-59-1 2-(3-hydroxypropylamino)-1-phenacylbenzimidazole hydrobromide 
• 292613-90-2 {3-[2-(4-chloro-phenyl)-1,3a,8-triaza-cyclopenta[a]inden-1-yl]-propyl}-diethyl-amine 
• 331971-09-6 3-{2-(4-bromophenyl)-1H-imidazo[1,2-a]benzimidazol-1-yl}propan-1-ol 
• 301168-45-6 3-{2-(4-chlorophenyl)-1H-imidazo[1,2-a]benzimidazol-1-yl}propan-1-ol 

Relevant academic research and scientific papers

Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors

Phosphodiesterase 10A (PDE10A) inhibitors were designed and synthesized based on the dihydro-imidazobenzimidazole scaffold. Compound 5a showed moderate inhibitory activity and good permeability, but unfavorable high P-glycoprotein (P-gp) liability for bra

Research in the field of imidazo[1,2-a]benzimidazole derivatives: XXVII. 1-acylmethyl-2-(ω-hydroxyalkylamino)-benzimidazoles and their transformation into derivatives of tricyclic systems

1-Acylmethyl-2-(ω-hydroxyalkylamino)benzimidazoles were synthesized and their behavior under various conditions was investigated: at the thermolysis without solvent, at heating in DMF or in 2-aminoethanol, hydrohalic acids, and acetic anhydride, in the presence of chlorinating agents (SOCl2, POCl3). Depending on the reaction conditions derivatives were obtained of 1H-imidazo[1,2-a]-benzimidazole, 9H-2,3-dihydroimidazo[1,2-a] benzimidazole, and 10H-2,3,4,10-tetrahydropyrimido[1,2-a]-benzimidazole that were suitable synthons for the synthesis of functionally substituted derivatives of these tricyclic systems.

Benzimidazole compounds

Compounds of the general formula (I): STR1 wherein A, B, C, D, n, R1, R2, R3, R4, X, Y and Z are as defined in the description, and their use as antidiabetics are disclosed.