1541175-16-9Relevant articles and documents
Potassium trinitromethanide as a 1,1-ambiphilic synthon equivalent: Access to 2-nitroarenofurans
Osyanin, Vitaly A.,Osipov, Dmitry V.,Demidov, Maxim R.,Klimochkin, Yuri N.
, p. 1192 - 1198 (2014/03/21)
The first example of the use of potassium trinitromethanide as a 1,1-ambiphilic synthon equivalent for the construction of a benzofuran moiety mediated by triethylamine has been developed. The method tolerates a variety of functional groups on the starting quaternary ammonium salt and has been successfully extended to polysubstituted benzofurans. Formation of an o-quinone methide intermediate is postulated as a key to the mechanism of this cascade process.
