154118-41-9Relevant academic research and scientific papers
Configuration and conformational study of some 2-aryl-trans-decahydroquinolin-4-ones
Bhavani,Natarajan
, p. 582 - 586 (2007/10/03)
The assignments of the proton and carbon signals and conformations of substituted 2-aryl-trans-decahydroquinolin-4-ones were determined using a combination of 1H, 13C, COSY and HETCOR spectral data. Analysis of the spectral data reveals that these compounds exist predominantly in twin-chair conformations with the aryl and alkyl substituents in the equatorial orientation. Introduction of an alkyl group at C-3 causes a flattening of the ring about the C-2 - C-3 bond. From the proton-proton coupling constants (J9, 10,) the junction between the rings is found to be trans.
