1541193-41-2

Upstream product

• 13291-18-4 isopropenylmagnesium bromide 
• 183894-33-9 (R)-(+)-1-[(3'-iodo-2'-methylpropoxy)methyl]-4-methoxybenzene 

Downstream Products

• 1541193-51-4 (2S,4S)-5-(4-methoxyphenoxy)-2,4-dimethylpentane-1,2-diol 
• 1541193-49-0 (2R,4S)-5-(4-methoxyphenoxy)-2,4-dimethylpentane-1,2-diol 
• 1541193-50-3 (2S,4S)-5-(4-methoxybenzyloxy)-2,4-dimethylpentane-1,2-diol 
• 1541193-48-9 (2S,4R)-5-(4-methoxybenzyloxy)-2,4-dimethylpentane-1,2-diol 
• 1541193-42-3 (S)-1-((2,4-dimethylpent-4-en-1-yl)oxy)-4-methoxybenzene 

Relevant academic research and scientific papers

Asymmetric sharpless dihydroxylation reaction of chiral bishomoallylic alcohols: Application to the synthesis of the C1-C10-C5 fragment of FR225654

Toward the synthesis of FR225654, an antidiabetic natural product, the Sharpless asymmetric dihydroxylation of chiral bishomoallylic alcohols, never reported in the literature, was examined. Employing the pyrimidine class of ligands, a high level of matched diastereoselectivity was obtained. An application to the stereoselective synthesis of the C1-C10-C5 fragment of FR225654 was performed. Georg Thieme Verlag Stuttgart · New York.