154155-20-1Relevant academic research and scientific papers
Cytotoxicity and Antiviral Activity of Transition-metal Salicylato Complexes and Crystal Structure of Bis(diisopropylsalicylato)(1,10-phenanthroline)copper(II)
Ranford, John D.,Sadler, Peter J.,Tocher, Derek A.
, p. 3393 - 3400 (1993)
Complexes of Cu(II), Fe(III), Co(II), Ni(II), Ti(IV) and Zn(II) with 3,5-disubstituted salicylates, and ternary complexes of Cu(II) containing substituted phenanthrolines have been prepared and characterised.The crystal structure of bis(diisopropylsalicylato)(1,10-phenanthroline)copper(II), , has been determined; Cu(II) is in a tetragonal co-ordination environment with in-plane bonds to 2 nitrogens from phen and 2 oxygens from the carboxylates of Hdips , with weaker off-axial bonds to carboxylate oxygens .The hydroxyl oxygen of Hdips is not co-ordinated.These complexes have been tested for antiviral and cytotoxic activity.Most are potently cytotoxic, especially , where dmphen is 2,9-dimethylphenanthroline.
