15417-14-8Relevant academic research and scientific papers
1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE
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Page/Page column 44, (2010/04/03)
The present invention relates to compounds defined by formula (I) wherein the group R is defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11 β-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases.
SYNTHESIS OF FUNCTIONAL DERIVATIVES OF TRICYCLIC HYDROCARBONS
Butenko, L. N.,Protopopov, P. A.,Derbisher, V. E.,Khardin, A. P.
, p. 113 - 120 (2007/10/02)
The synthesis of carboxylic derivatives of the tricyclic hydrocarbons adamantane and trimethylenenorbornane by the treatment of the hydrocarbons with formic acid and vinylidene chloride in a mixture of sulfuric and nitric acid is described.
