15419-92-8Relevant academic research and scientific papers
Facile Synthesis of 1,2-Disubstituted Benzimidazoles Usingp-Toluenesulfonic Acid through Grinding Method
Kathing, C.,Nongkhlaw, R.,Nongrum, R.,Singh, N. G.,World Star Rani, J.
, p. 1628 - 1634 (2020/10/22)
Abstract: An efficient synthetic method for the highly selective synthesis ofpharmacologically active 1,2-disubstituted benzimidazole derivatives fromo-phenylenediamine and various aromaticaldehydes catalyzed by p-toluenesulfonic acidthrough grinding unde
γ-Maghemite-silica nanocomposite: A green catalyst for diverse aromatic N-heterocycles
Ghosh, Pranab,Mandal, Amitava,Subba, Raju
, p. 146 - 152 (2013/09/02)
γ-Maghemite-silica nanocomposite has been applied as a green catalyst to synthesize variety of aromatic N-heterocycles under solvent free conditions. Characterization was done by modern analytical tools (UV, IR, AAS, DSC, EDXRF, powdered XRD, EPR, Mo?ssbauer and TEM). Mild reaction conditions and recyclability have made the present protocol both environmentally and economically viable.
Synthesis, characterization and biological activity of some platinum(II) complexes with Schiff bases derived from salicylaldehyde, 2-furaldehyde and phenylenediamine
Gaballa, Akmal S.,Asker, Mohsen S.,Barakat, Atiat S.,Teleb, Said M.
, p. 114 - 121 (2008/02/03)
Four platinum(II) complexes of Schiff bases derived from salicylaldehyde and 2-furaldehyde with o- and p-phenylenediamine were reported and characterized based on their elemental analyses, IR and UV-vis spectroscopy and thermal analyses (TGA). The complex
Cyanide-Catalyzed Cyclizations via Aldimine Coupling
Reich, B. Jesse E.,Justice, Aaron K.,Beckstead, Brittany T.,Reibenspies, Joseph H.,Miller, Stephen A.
, p. 1357 - 1359 (2007/10/03)
Aldimine coupling (AIC) is the nitrogen analogue of the benzoin condensation and has been applied to dialdimines, providing the first examples of cyclizations effected by cyanide-catalyzed AIC. Sodium cyanide promoted the facile, intramolecular cyclization of several dialdimines in N,N-dimethylformamide, methanol, or methylene chloride/water (phase-transfer conditions) yielding a variety of six-membered heterocycles. Under aerobic conditions, an oxidative cyclization occurs to provide the diimine heterocycle. Oligomerization was observed with rigid dialdimines for which cyclization was precluded.
Cobalt(II)-Catalyzed Conversion of Allylic Alcohols/Acetates to Allylic Amides in the Presence of Nitriles
Mukhopadhyay, Manoj,Reddy, M. Madhava,Maikap, G. C.,Iqbal, Javed
, p. 2670 - 2676 (2007/10/02)
Various secondary allylic alcohols or their acetates and tertiary allylic alcohols can be converted to the corresponding transposed allylic amides in the presence of a catalytic quantity of cobalt(II) chloride and acetic anhydride in acetonitrile.Tertiary alcohols undergo complete rearrangement whereas secondary ones afford a mixture of regioisomers.Moderate yields of amides are also obtained by reacting acrylonitrile with secondary alcohols in 1,2-dichloroethane.The presence of acetic anhydride or acetic acid is crucial to the formation of amides as the absence of the former affords no amides and the allylic alcohols are mainly recovered as regioisomeric mixtures.The regioselectivity during amide formation can be enhanced by using cobalt complexes 14-16 in acetic acid medium.Some preliminary studies indicate that these reactions are proceeding via an ?-allyl complex or tight ion pair rather than a sigmatropic rearrangement of acetamidate obtained in a Pinner reaction.
