154194-69-1

Basic information

• Product Name: N-Acetyl--alanine N-Hydroxysuccinimide Ester
• Synonyms: N-Acetyl--alanine N-Hydroxysuccinimide Ester;N-[3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]acetaMide;(2,5-Dioxopyrrolidin-1-yl) 3-acetamidopropanoate
• CAS NO: 154194-69-1
• Molecular Formula: C9H12N2O5
• Molecular Weight: 228.20198
• Product Categories: Amino Acids & Derivatives;Heterocycles;Intermediates
• Mol File: 154194-69-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 82-84°C
• Appearance: /
• Density: 1.35±0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20?C Freezer, Under Inert Atmosphere
• Solubility: Chloroform, DMSO, Ethyl Acetate, Methanol
• PKA: 15.55±0.46(Predicted)
• CAS DataBase Reference: N-Acetyl--alanine N-Hydroxysuccinimide Ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Acetyl--alanine N-Hydroxysuccinimide Ester(154194-69-1)
• EPA Substance Registry System: N-Acetyl--alanine N-Hydroxysuccinimide Ester(154194-69-1)

Safety Data

• Hazardous Substances Data: 154194-69-1(Hazardous Substances Data)

Usage

Chemical Properties

Light Yellow Liquid

Uses

Intermediate in the preparation of polyamide inducers of HL-60 cellular differentiation

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 3025-95-4 N-acetyl-β-alanine 

Relevant articles and documents

Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides

Pyrrole-imidazole (Py-Im) polyamides are a group of chemicals that are able to bind specifically to DNA sequences in vitro and in mammalian cells. Using a cell based reporter assay, we investigated the size and linker affects on the cellular permeability