154197-07-6

Basic information

• Product Name: methyl 4-chlorobenzylphosphonyl chloride
• Synonyms: methyl 4-chlorobenzylphosphonyl chloride
• CAS NO: 154197-07-6
• Molecular Weight: 239.038
• Mol File: 154197-07-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-chlorobenzylphosphonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-chlorobenzylphosphonyl chloride(154197-07-6)
• EPA Substance Registry System: methyl 4-chlorobenzylphosphonyl chloride(154197-07-6)

Safety Data

• Hazardous Substances Data: 154197-07-6(Hazardous Substances Data)

Upstream product

• 622-95-7 4-chlorobenzyl bromide 
• 58358-45-5 p-Chlorobenzylphosphonsaeuredimethylester 

Downstream Products

• 154196-94-8 4-methoxyphenyl methyl 4-chlorobenzylphosphonate 

Relevant articles and documents

Tetrahydroquinolinyl phosphinamidates and phosphonamidates enhancing tolerance towards drought stress in crops via interaction with ABA receptor proteins

New phosphorous-containing lead structures against drought stress in crops interacting with RCAR/(PYR/PYL) receptor proteins were identified starting from in-depth SAR studies of related sulfonamide lead structures and protein docking studies. A converging 6-step synthesis via phosphinic chlorides and phosphono chloridates as key intermediates afforded envisaged tetrahydroquinolinyl phosphinamidates and phosphonamidates. Whilst tetrahydroquinolinyl phosphonamidates 13a,b exhibited low to moderate target affinities, the corresponding tetrahydroquinolinyl phosphinamidates 12a,b revealed confirmed strong affinities for RCAR/ (PYR/PYL) receptor proteins in Arabidopsis thaliana on the same level as essential plant hormone abscisic acid (ABA) combined with promising efficacy against drought stress in vivo (broad-acre crops wheat and canola).