58358-45-5

Basic information

• Product Name: Phosphonic acid, [(4-chlorophenyl)methyl]-, dimethyl ester
• Synonyms: dimethyl 4-chlorobenzylphosphonate;p-Chlorobenzylphosphonsaeuredimethylester
• CAS NO: 58358-45-5
• Molecular Formula: C9H12ClO3P
• Molecular Weight: 234.619
• Mol File: 58358-45-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [(4-chlorophenyl)methyl]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [(4-chlorophenyl)methyl]-, dimethyl ester(58358-45-5)
• EPA Substance Registry System: Phosphonic acid, [(4-chlorophenyl)methyl]-, dimethyl ester(58358-45-5)

Safety Data

• Hazardous Substances Data: 58358-45-5(Hazardous Substances Data)

Upstream product

• 868-85-9 Dimethyl phosphite 
• 873-76-7 para-Chlorobenzyl alcohol 
• 121-45-9 phosphorous acid trimethyl ester 
• 622-95-7 4-chlorobenzyl bromide 
• 186581-53-3 diazomethane 
• 154197-03-2 bis(4-methoxyphenyl) 4-chlorobenzylphosphonate 
• 154197-00-9 3-cyano-4'-methoxybiphenyl 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 

Downstream Products

• 147137-69-7 4-chlorobenzylphosphonyl dichloride 
• 154197-07-6 methyl 4-chlorobenzylphosphonyl chloride 
• 181575-52-0 methyl p-chlorobenzylphosphonate 
• 60754-00-9 C₁₅H₁₂ClNO₂ 
• 60753-98-2 1-((E)-1-(4-chlorophenyl)prop-1-en-2-yl)benzene 
• 60753-99-3 C₁₅H₁₂BrCl 
• 154702-26-8 methyl dimethoxyphosphoryl(4-chlorophenyl)acetate 
• 78022-15-8 1-(4-Chlorostyryl)-4-(2-cyanostyryl)benzene 
• 154197-03-2 bis(4-methoxyphenyl) 4-chlorobenzylphosphonate 
• 154196-94-8 4-methoxyphenyl methyl 4-chlorobenzylphosphonate 
• 617714-57-5 3-(4-Chloro-benzylidene)-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester 
• 60754-01-0 2-[(E)-2-(4-Chloro-phenyl)-1-methyl-vinyl]-1,3,5-trimethyl-benzene 

Relevant articles and documents

Tetrahydroquinolinyl phosphinamidates and phosphonamidates enhancing tolerance towards drought stress in crops via interaction with ABA receptor proteins

New phosphorous-containing lead structures against drought stress in crops interacting with RCAR/(PYR/PYL) receptor proteins were identified starting from in-depth SAR studies of related sulfonamide lead structures and protein docking studies. A converging 6-step synthesis via phosphinic chlorides and phosphono chloridates as key intermediates afforded envisaged tetrahydroquinolinyl phosphinamidates and phosphonamidates. Whilst tetrahydroquinolinyl phosphonamidates 13a,b exhibited low to moderate target affinities, the corresponding tetrahydroquinolinyl phosphinamidates 12a,b revealed confirmed strong affinities for RCAR/ (PYR/PYL) receptor proteins in Arabidopsis thaliana on the same level as essential plant hormone abscisic acid (ABA) combined with promising efficacy against drought stress in vivo (broad-acre crops wheat and canola).

Palladium(II)-catalyzed ortho-arylation of benzylic phosphonic monoesters using potassium aryltrifluoroborates

The new monophosphonic acid directing group was successfully utilized in the Pd (II)-catalyzed ortho-arylation of benzylic phosphonic monoesters using potassium aryltrifluoroborates. A wide range of benzylic phosphonic monoesters underwent clean ortho-ary

Photolysis of 4-Methoxyphenyl Aryl Alkylphosphonates

UV irradiation of bis(4-methoxyphenyl) methylphosphonate 1a in methanol gave 4,4'-dimethoxybiphenyl 2a as the main product through an intramolecular excimer.With 4-cyanophenyl-4-methoxyphenyl methylphosphonate 1b 4-cyano-4'-methoxybiphenyl 2c and 4-cyano-2-(4'-methoxyphenyl)phenyl methylphosphonate 4b were obtained through an intramolecular exciplex. 3-Cyanophenyl-4-methoxyphenyl methyl phosphonate 1c gave only 3-cyano-4'-methoxybiphenyl 2f.Methyl 4-methoxyphenyl 4-chlorobenzylphosphonate 5a gave dimethyl 4-chlorobenzyl 2-(4'-methoxyphenyl)phosphonate and dimethyl 2-(4'-methoxyphenyl)benzylphosphonate.