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15421-84-8

15421-84-8

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15421-84-8 Usage

Chemical Properties

White or almost white, crystalline powder

Originator

Rocornal,Mochida,Japan,1978

Uses

Vasodilator;PDGF antagonist

Manufacturing Process

8.4 g of 5-methyl-7-chloro-s-triazolo-(1,5-a)-pyrimidine were suspended in 30 cc of water and 7.3 g of diethylamine added. After 2 hours heating with stirring, the mixture was concentrated under vacuum. The residue was recrystallized from n-heptane. This process yielded 8.1 g of the 5-methyl-7- diethylamino-s-triazolo-(1,5-a)-pyrimidine having a melting point of 103°C to 104°C. The hydrochloride produced in the usual manner had a melting point of 212°C.

Therapeutic Function

Coronary vasodilator

Safety Profile

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. An experimental teratogen. Other experimental reproductive effects. A coronary vasodilator. When heated to decomposition it emits toxic fumes of NOx. See also MINES.

Check Digit Verification of cas no

The CAS Registry Mumber 15421-84-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,2 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 15421-84:
(7*1)+(6*5)+(5*4)+(4*2)+(3*1)+(2*8)+(1*4)=88
88 % 10 = 8
So 15421-84-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H15N5/c1-4-14(5-2)9-6-8(3)13-10-11-7-12-15(9)10/h6-7H,4-5H2,1-3H3

15421-84-8 Well-known Company Product Price

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  • Sigma-Aldrich

  • (T1820000)  Trapidil  European Pharmacopoeia (EP) Reference Standard

  • 15421-84-8

  • T1820000

  • 1,880.19CNY

  • Detail

  • Sigma

  • (SML0071)  Trapidil  ≥98% (HPLC)

  • 15421-84-8

  • SML0071-10MG

  • 1,099.80CNY

  • Detail

  • Sigma

  • (SML0071)  Trapidil  ≥98% (HPLC)

  • 15421-84-8

  • SML0071-50MG

  • 4,437.81CNY

  • Detail

15421-84-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

1.2 Other means of identification

Product number -
Other names (1,2,4)Triazolo(1,5-a)pyrimidin-7-amine,N,N-diethyl-5-methyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15421-84-8 SDS

15421-84-8Downstream Products

15421-84-8Relevant articles and documents

CD40 signal blocking agent

-

, (2008/06/13)

A CD40 signal blocking agent comprising, as an active ingredient, s-triazolo[1,5-a]pyrimidine derivative represented by the following formula (1) or a pharmaceutically acceptable salt thereof, is disclosed

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