1542168-64-8

Basic information

• Product Name: N-[(3α)-23-(1,3-dimethyl-1,2,5,6-tetrahydropyridin-4-yl)-24-nor-5α,22E-chola-7,22-dien-3-yl]-N-methyl-2-nitrobenzenesulfonamide
• Synonyms: N-[(3α)-23-(1,3-dimethyl-1,2,5,6-tetrahydropyridin-4-yl)-24-nor-5α,22E-chola-7,22-dien-3-yl]-N-methyl-2-nitrobenzenesulfonamide
• CAS NO: 1542168-64-8
• Molecular Weight: 635.912
• Mol File: 1542168-64-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[(3α)-23-(1,3-dimethyl-1,2,5,6-tetrahydropyridin-4-yl)-24-nor-5α,22E-chola-7,22-dien-3-yl]-N-methyl-2-nitrobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(3α)-23-(1,3-dimethyl-1,2,5,6-tetrahydropyridin-4-yl)-24-nor-5α,22E-chola-7,22-dien-3-yl]-N-methyl-2-nitrobenzenesulfonamide(1542168-64-8)
• EPA Substance Registry System: N-[(3α)-23-(1,3-dimethyl-1,2,5,6-tetrahydropyridin-4-yl)-24-nor-5α,22E-chola-7,22-dien-3-yl]-N-methyl-2-nitrobenzenesulfonamide(1542168-64-8)

Safety Data

• Hazardous Substances Data: 1542168-64-8(Hazardous Substances Data)

Upstream product

• 583-58-4 3,4-Lutidin 
• 23738-34-3 (3S,20S)-20-formyl-5α-pregn-7-en-3-yl-acetate 
• 1542168-54-6 (3β)-acetoxy-23-(3-methylpyridin-4-yl)-24-nor-5α,22E-chola-7,22-diene 
• 1542168-61-5 (3β)-hydroxy-23-(3-methylpyridin-4-yl)-24-nor-5α,22E-chola-7,22-diene 
• 1542168-62-6 N-methyl-N-[(3α)-23-(3-methylpyridin-4-yl)-24-nor-5α,22E-chola-7,22-dien-3-yl]-2-nitrobenzenesulfonamide 
• 1542168-63-7 4-[(3α)-(N-methyl-2-nitrobenzylsulfamoyl)-24-nor-5α,22E-chola-7,22-dien-23-yl]-1,3-dimethylpyridinium iodide 

Relevant articles and documents

First total synthesis of the marine steroid alkaloid plakinamine B

The first total synthesis of the marine steroid alkaloid plakinamine B (1) was accomplished in seven steps starting from known aldehyde 3. Key steps in this synthesis are the attachment of a vinylpyridine side chain by an aldol reaction, a chemoselective reduction of a pyridinium salt to a vinyl tetrahydropyridine, and the introduction of the 3α-methylamino group under Mitsunobu conditions. Plakinamine B and some of its precursors with amino or pyridinium side chains show significant antimicrobial activities.