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1542268-31-4

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1542268-31-4 Usage

Uses

(3R,5R)-3,5-Dimethylmorpholine Hydrochloride is used in the preparation KIF18A inhibitors for the treatment of cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 1542268-31-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,4,2,2,6 and 8 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1542268-31:
(9*1)+(8*5)+(7*4)+(6*2)+(5*2)+(4*6)+(3*8)+(2*3)+(1*1)=154
154 % 10 = 4
So 1542268-31-4 is a valid CAS Registry Number.

1542268-31-4Downstream Products

1542268-31-4Relevant articles and documents

(S,S)-3,5-dimethylmorpholine, a novel C2-symmetric auxiliary. First application in [4 + 2]-cycloadditions leading to 4-oxohexahydropyridazine derivatives

Enders,Meyer,Raabe,Runsink

, p. 66 - 72 (1994)

Diastereoselective Diels-Alder reactions of (S,S)-2-(3,5-dimethylmorpholino)butadienes 10 with aza-dienophiles are described, leading to cycloadducts 12 in good yields and high stereoselectivities (de = 87-96%). After double bond migration to 13, acidic a

TRIAZOLYL DERIVATIVES AS SYK INHIBITORS

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Page/Page column 93, (2014/04/17)

Provided are triazole derivatives of Formula I which are potent inhibitors of spleen tyrosine kinase and pharmaceutical composition. The triazole derivatives are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.

VLA-4 INHIBITORY DRUG

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Page/Page column 144, (2008/12/08)

There is provided a VLA-4 inhibitory drug having good oral absorbability and exhibiting sufficient anti-inflammatory effects when administered orally. A compound represented by the following formula (I): wherein R1 represents a hydrogen atom or a C1-8 alkyl group; R2 represents a hydrogen atom, a halogen atom, a C1-8 alkoxy group, orabenzyloxygroupwhichmaybe substituted; Q represents a monocyclic or bicyclic nitrogen-containing heterocyclic group which may be substituted, and has a nitrogen atom as the bonding site; Y represents an oxygen atom or CH2; W represents a bicyclic aromatic hydrocarbon ring group which may be substituted, or a bicyclic aromatic heterocyclic group whichmaybe substituted; R3a, R3b and R3c each independently represent a hydrogen atom, a halogen atom, a C1-8 alkoxy group or a C1-8 alkyl group; and A1 represents a nitrogen atom or C-R3d (wherein R3d represents a hydrogen atom, a halogen atom, a C1-8 alkoxy group or a C1-8 alkyl group), or a salt thereof, or a VLA-4 inhibitory drug comprising the compound or the salt as an active ingredient.

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