154255-39-7

Upstream product

• 103-84-4 Acetanilid 
• 54-85-3 isoniazid 
• 73568-25-9 2-chloro-3-quinoline carboxaldehyde 
• 613-94-5 benzoic acid hydrazide 

Downstream Products

• 1397263-11-4 C₂₄H₁₇Cl₂N₅O 
• 1397263-12-5 C₂₄H₁₇Cl₂N₅O 
• 1397263-14-7 C₂₄H₁₇ClN₆O₃ 
• 1397263-15-8 C₂₄H₁₇ClN₆O₃ 
• 1397263-16-9 C₂₄H₁₇ClN₆O₃ 
• 1397263-17-0 C₂₅H₂₀ClN₅O₂ 
• 1397263-18-1 C₂₅H₂₀ClN₅O₂ 
• 1397263-19-2 C₂₅H₂₀ClN₅O₂ 
• 1397263-21-6 C₂₄H₁₇ClFN₅O 
• 1397263-22-7 C₂₄H₁₇ClFN₅O 
• 1397263-13-6 4-chloro-N-(1-(2-(2-chloroquinolin-3-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl)ethylidene)aniline 
• 1397263-23-8 3-chloro-1-(2-chlorophenyl)-4-(2-(2-chloroquinolin-3-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl)-4-methylazetidin-2-one 
• 1397263-24-9 3-chloro-1-(3-chlorophenyl)-4-(2-(2-chloroquinolin-3-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl)-4-methylazetidin-2-one 
• 1397263-25-0 3-chloro-1-(4-chlorophenyl)-4-(2-(2-chloroquinolin-3-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl)-4-methylazetidin-2-one 

Relevant academic research and scientific papers

Synthesis, characterization, and antimicrobial evaluation of quinoline-oxadiazole-based azetidinone derivatives

A series of 3-chloro-1-(aryl)-4-(2-(2-chloroquinolin-3-yl)-5-(pyridin-4-yl) -1,3,4-oxadiazol-3(2H)-yl)-4-ethyl-azetidin-2-ones (5a-l) have been synthesized and characterized by IR, 1H NMR, and13C NMR. Synthesized compounds were screened for their antimicrobial activity against different strains of bacteria (E. coli, P. aeruginosa, S. aureus, S. pyogenes, C. albicans, A. niger, and A. clavatus). On the basis of statistical analysis, it has been observed that compounds had significant correlations.

A "green" synthesis of N-(quinoline-3-ylmethylene)benzohydrazide derivatives and their cytotoxicity activities

We report some hybrid molecules based on N-(quinoline-3-ylmethylene) benzohydrazide template the synthesis of which was carried out using 2-chloroquinoline-3-carbaldehyde and a variety of substituted hydrazides in PEG 400. The "green" solvent PEG 400 was recovered and reused for several times in the present reaction and was found to be effective in terms of product yield. Some of the compounds synthesized showed significant cytotoxic activity when tested in vitro. ?2011 Sociedade Brasileira de Qui?mica.

Synthesis and antimicrobial evaluation of novel oxa(thia)diazolylquinolines and oxa(thia)diazepino[7,6-b] quinolines

Three novel series of quinoline derivatives have been prepared by cyclization of the intermediate 3[(substituted)thiocarbamoyl-hydrazonomethyl]-2-chloroquinolines and 3-aroylhydrazonomethyl-2-chloroquinolines: 3-(3-Acetyl-5-(substituted)-2,3-dihydro-1,3,4-oxa(thia)diazol-2-yl)-2- chloroquinolines(4; 5), 3-(5-(substituted)-1,3,4-oxa(thia)diazol-2-yl)-2-chloroquinolines (6; 7), and 2-(substituted)-1,3,4-oxa(thia)diazepino[7,6-b]quinolines (8; 9). The antimicrobial activity of these compounds was studied.