154279-16-0 Usage
General Description
(±)-N-Boc-2-amino-2-benzylacetonitrile is a chemical compound with the molecular formula C16H21N3O2. It is a nitrile derivative with a benzyl group and a Boc-protected amino group. (±)-N-Boc-2-amino-2-benzylacetonitrile is often used in organic synthesis as a building block for creating complex molecules, especially in the field of pharmaceutical and medicinal chemistry. The Boc protecting group can be removed under acidic conditions, allowing for further functionalization of the amino group. Its benzylacetonitrile moiety provides reactivity towards many organic reactions, making it a versatile intermediate in the production of a wide range of compounds. The compound is stable under normal conditions and can be handled safely in a laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 154279-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,2,7 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 154279-16:
(8*1)+(7*5)+(6*4)+(5*2)+(4*7)+(3*9)+(2*1)+(1*6)=140
140 % 10 = 0
So 154279-16-0 is a valid CAS Registry Number.
154279-16-0Relevant articles and documents
Decarboxylative Cyanation of Aliphatic Carboxylic Acids via Visible-Light Flavin Photocatalysis
Ramirez, Nieves P.,K?nig, Burkhard,Gonzalez-Gomez, Jose C.
supporting information, (2019/03/08)
An operationally simple method is disclosed for the decarboxylative cyanation of aliphatic carboxylic acids at room temperature. Riboflavin tetraacetate, which is an inexpensive organic photocatalyst, promotes the oxidation of carboxylic acids upon visible-light activation. After decarboxylation, the generated radicals are trapped by TsCN, yielding the desired nitriles without any further additive, in a redox-neutral process. Importantly, this protocol can be adapted to flow conditions.
α-Isocyanatoacrylonitriles from alkylidene- or arylidenecyanoacetic acids; synthesis and reactions
Jaafar,Francis,Danion-Bougot,Danion
, p. 56 - 60 (2007/10/02)
The Curtius reaction converts alkylidene- or arylidenecyanoacetic acids to α-isocyanatoacrylonitriles in a stereospecific way. These versatile intermediates allow an easy access to arylacetic acids and various amino acid derivatives, as well as β-lactams or 2-azabutadienes.
