15431-85-3

Usage

Uses

Used in Organic Synthesis:
1H-Pyrrole, 1-benzoyl-2,5-dihydrois used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure allows for the formation of various derivatives, which can be further utilized in the development of new compounds with specific properties and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1H-Pyrrole, 1-benzoyl-2,5-dihydrois used as a starting material for the synthesis of drug candidates. Its structural features and potential biological activity make it a valuable compound for the development of new medications with therapeutic benefits.
Used in Agrochemical Industry:
1H-Pyrrole, 1-benzoyl-2,5-dihydrois also used in the agrochemical industry for the synthesis of agrochemicals, such as pesticides and herbicides. Its unique properties can contribute to the development of more effective and environmentally friendly products.
Used in Materials Science:
In materials science, 1H-Pyrrole, 1-benzoyl-2,5-dihydrois used for the development of new materials with specific properties, such as conductivity, stability, or reactivity. Its incorporation into various materials can lead to the creation of innovative products with improved performance.
Used in Drug Discovery and Development:
1H-Pyrrole, 1-benzoyl-2,5-dihydrois of interest to researchers as a potential target for drug discovery and development. Its unique structural features and potential biological activity make it a promising candidate for the development of new therapeutic agents with novel mechanisms of action.

Upstream product

• 10283-70-2 N,N-diallylbenzamide 
• 18866-73-4 cis-1,4-dibromo-2-butene 
• 55-21-0 benzamide 
• 1310558-69-0 N-(buta-2,3-dien-1-yl)benzamide 
• 98-88-4 benzoyl chloride 

Downstream Products

• 3389-54-6 n-benzoylpyrrolidine 
• 72351-43-0 N-benzoyl-2-pyrrolidinecarbaldehyde 
• 195719-48-3 N-benzoylproline 

Relevant academic research and scientific papers

Olefin metathesis featuring ruthenium indenylidene complexes with a sterically demanding NHC ligand

The synthesis and characterization of two new ruthenium indenylidene complexes [RuCl2(SIPr)(Py)(Ind)] 6 and [RuCl2(SIPr)(3- BrPy)(Ind)] 7 featuring the sterically demanding N-heterocyclic carbene 1,3-bis(2,6-di isopropylphenyl)-4,5-d

Ring-closing metathesis in biphasic BMI·PF6 ionic liquid/toluene medium: A powerful recyclable and environmentally friendly process

Biphasic BMI·PF6/toluene solvent is a remarkably suitable and clean medium for performing olefin metathesis with a new 2nd generation ionic liquid supported-ruthenium catalyst: high levels of recyclability and reusability combined with a high r

Ring-closing metathesis at room temperature within nanometer micelles using water as the only solvent

Simply mixing a water-insoluble diolefinic substrate and Grubbs second generation catalyst in pure water containing small amounts of the amphiphile polyoxyethanyl α-tocopheryl sebacate (PTS) leads to efficient ring-closing metathesis.

Modified routes to the "designer" surfactant PQS

Described herein are newly developed, straightforward entries to polyethyleneglycol ubiquinol succinate (PQS, n = 2), a designer surfactant that serves as precursor to micelle-forming, covalently bound catalysts for a variety of transformations in water w

Activated pyridinium-tagged ruthenium complexes as efficient catalysts for ring-closing metathesis

New pyridinium-tagged ruthenium catalysts have been synthesised to perform olefin metathesis in several media including both organic and aqueous solvents and room temperature ionic liquids (RTILs). High activity was obtained in the ring-closing metathesis (RCM) of a variety of di- or tri-substituted and/or oxygen-containing dienes. However, only fair levels of recycling combined with low to moderate residual ruthenium levels (25-173 ppm) have been observed showing clearly the difficulty of associating high activity and recyclability.

Synthesis of Vanadium Oxo Alkylidene Complex and Its Reactivity in Ring-Closing Olefin Metathesis Reactions

V imido alkylidenes have been applied for the ring-opening metathesis polymerization involving cyclic olefins. However, those complexes found limited application in reactions with acyclic terminal olefins due to instability toward ethylene. Experimental and theoretical studies show that the β-hydride elimination from unsubstituted metallacyclobutene is the primary decomposition pathway in those systems. Herein, we report the synthesis of the first catalytically active V oxo alkylidene, VO(CHSiMe3)(PEt3)2Cl, which exhibits the highest reported productivity with various terminal olefins in ring-closing metathesis reactions among known V catalysts. Presented DFT studies indicate that β-hydride elimination is significantly disfavored for V oxo species.

Ring-Closing Olefin Metathesis Catalyzed by Well-Defined Vanadium Alkylidene Complexes

Vanadium-based catalysts have shown activity and selectivity in ring-opening metathesis polymerization of strained cyclic olefins comparable to those of Ru, Mo, and W catalysts. However, the application of V alkylidenes in routine organic synthesis is limited. Here, we present the first example of ring-closing olefin metathesis catalyzed by well-defined V chloride alkylidene phosphine complexes. The developed catalysts exhibit tolerance to various functional groups, such as an ether, an ester, a tertiary amide, a tertiary amine, and a sulfonamide. The size and electron-donating properties of the imido group and the phosphine play a crucial role in the stability of active intermediates. Reactions with ethylene and olefins suggest that both β-hydride elimination of the metallacyclobutene and bimolecular decomposition are responsible for catalyst degradation.

Synthesis of N -Sulfonyl- and N -Acylpyrroles via a Ring-Closing Metathesis/Dehydrogenation Tandem Reaction

N -Sulfonyl- and N -acylpyrroles were synthesized via olefin ring-closing metathesis of diallylamines and in situ oxidative aromatization in the presence of the ruthenium Grubbs catalyst and a suitable copper catalyst. In the presence of Cu(OTf) 2/s

Nitrogen-coordination-containing ruthenium carbene catalyst and preparation method and application thereof

The present invention discloses a nitrogen-coordination-containing ruthenium carbene catalyst and a preparation method and application thereof. The nitrogen-coordination-containing ruthenium carbene catalyst is characterized by being shown in a formula (I

A pH-controlled recyclable indolinooxazolidine tagged N-heterocyclic carbene Ru catalyst for olefin metathesis

An indolinooxazolidine tagged N-heterocyclic carbene Ru olefin metathesis catalyst was synthesized and the molecular structure of this new Ru complex was determined by single crystal X-ray diffraction. This complex is a homogeneous catalyst and can be recovered by controlling the polarity of the indolinooxazolidine tag. Under acidic conditions the indolinooxazolidine tag exists as an open protonated form and under basic conditions the tag is in a closed form. The distribution of this catalyst in a two-phase system can be controlled by simply changing the pH, making the recovery of this catalyst easily obtainable.