154334-44-8

Upstream product

• 93303-74-3 (1S,2R)-2-benzylamino-1-phenylpropan-1-ol 
• 40626-29-7 Acutrim 
• 100-52-7 benzaldehyde 
• 37577-28-9 (1S,2R)-(+)-norphedrine 

Downstream Products

• 154257-51-9 (3R,4S)-3-methyl-4-phenyl-3,4-dihydroisoquinoline 

Relevant academic research and scientific papers

Asymmetric Epoxidation of Unfunctionalized Olefins Using Novel Chiral Dihydroisoquinolinium Salts as Organocatalysts

Abstract: Two new non-racemic chiral dihydroisoquinolinium salts with N-substituents bulkier than a methyl group have been synthesized from (1S,2R)-norephedrine. These salts were used to catalyze asymmetric epoxidation of a series of prochiral olefins. One of the two new catalysts provided higher enantioselectivities (up to 66% ee) than the reference salt containing an N-methyl substituent.

Oxygen atom transfer from a chiral oxaziridinium salt. Asymmetric epoxidation of unfunctionalized olefins

The synthesis of an optically pure oxaziridinium salt from (1S,2R)-(+)- norephedrine and the study of the asymmetric oxygen transfer reactions from this reagent to unfunctionalized olefins are described.

The Stereospecific Synthesis of a New Chiral Oxaziridinium Salt.

A new chiral oxaziridinium salt has been prepared from (1S,2R)-(+)-norephedrine.Enantioselective oxygen transfers to prochiral olefins and sulfides may be performed either stoichiometrically or in a catalytic cycle.