154343-07-4Relevant academic research and scientific papers
Unusual diastereoselection in the synthesis of nine-membered ring lactams and conformation-controlled transannular reactions to generate optically active indolizidinones
Sudau, Alexander,Nubbemeyer, Udo
, p. 1140 - 1143 (2007/10/03)
The aza-Claisen rearrangement of vinylpyrrolidines 1 yielded almost exclusively the trans-3,8-disubstituted nine-membered ring lactams 2 (TBS = tBuMe2Si), independent of whether cis or trans isomers were used as starting materials. The conforma
