154343-56-3Relevant articles and documents
Synthesis of 5,8-Dimethoxy-2(1H)-quinolinones by Intramolecular Wittig Reaction
Ferrer, Pedro,Avendano, Carmen,Soellhuber, Monica
, p. 1895 - 1900 (2007/10/03)
The title compounds 12, which are key intermediates for antitumoral diazaquinomycin A analogues, are obtained by intramolecular Wittig reaction of 1-alkyltriphenylphosphonium salts 11, which are prepared via lithiation of 2',5'-dimethoxy-N-pivaloylaniline 6.The applicability of this route to polysubstituted 2(1H)-quinolinones 12 and 17 is examined. - Keywords: Wittig reaction / 2(1H)-Quinolinones / ortho-Directed metalation of anilides