15438-85-4

Usage

Chemical classification

Derivative of 1,3,5-triazine (a heterocyclic aromatic compound)

Applications

Production of dyes and pigments
Synthesis of pharmaceuticals and agrochemicals
Intermediate in the production of other chemicals

Chemical properties

Strong electron-donating properties

Usage

Commonly used in organic synthesis reactions

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 584-02-1 2-pentanol 

Relevant academic research and scientific papers

Synthesis and antiviral evaluation of some C3-symmetrical trialkoxy-substituted 1,3,5-triazines and their molecular geometry

As one of our projects, we here report some new molecular modifications of 2,4,6-trichloro-1,3,5-triazine (TCTAZ: 1) to symmetrical 2,4,6-trialkoxy- or 2,4,6-triaryloxy-substituted 1,3,5-triazine (TAZ) molecules, as well as the results of anti-herpes simplex virus type 1 (anti-HSV-1) activity evaluation of synthesized 2,4,6-trisubstituted TAZ derivatives. Among the tested 2,4,6-trisubstituted TAZ derivatives, we reconfirmed that a C3-symmetrical TAZ derivative, 4e, shows the highest level of anti-HSV-1 activity with a good selectivity index. In this paper, we also report the results of the preparation of newly targeted TAZ derivatives and the structure-activity relationships (SARs) of these trialkoxy-substituted TAZ derivatives and related compounds. The sugar recognition properties of C3-symmetrical TAZ derivative 4e are also described.