154390-32-6Relevant articles and documents
An improved method for the generation of imines and enamides. Application to the synthesis of 3-arylisoquinoline derivatives
Sotomayor, Nuria,Vicente, Teresa,Dominguez, Esther,Lete, Esther,Villa, Maria-Jesus
, p. 2207 - 2218 (1991)
The one-pot preparation of hindered 1,2-diarylethylamines 3 and 4 and ethylenenamides 5 is achieved via sodium cyanoborohydride reduction and acylation of the deoxybenzoin imines 2, respectively. A new methodology for the synthesis of 3-arylisoquinolinium salts by the Bischler-Napieralski reaction of 1,2-diarylethylenenamides and their transformation into 12-methyl substituted benzo[c]phenanthridines has been developed.