1544005-17-5

Upstream product

• 1400707-08-5 cyclopropyl [(3S,4R)-3-fluoropiperidin-4-yl]carbamic acid tert-butyl ester 
• 277756-46-4 1-(trifluoromethyl)cyclopropanecarboxylic acid 
• 1020934-33-1 3-fluoro-4-(1H-1,2,4-triazol-1-yl)benzoic acid 
• 1544006-04-3 (3S,4R)-N-cyclopropyl-3-fluoro-1-[1-(trifluoromethyl-cyclopropylmethyl)]-piperidin-4-amine 

Relevant academic research and scientific papers

N-CYCLOPROPYL-N-PIPERIDINYL-AMIDE DERIVATIVES AND THEIR USE AS GPR119 MODULATORS

The present invention relates to compounds of general formula I wherein R1 is selected from a group consisting of -CH2-Ra, wherein Ra denotes C1-6-alkyl optionally mono- or polysubstituted with fluorine, or C3-6- cycloalkyl optionally mono- or polysubstituted with fluorine and optionally substituted with a group selected from among CH3, CF3, and CHF2, and Lp, (Het)Ar1, (Het)Ar2 and n are as defined in the application, which have valuable pharmacological properties, and in particular bind to the GPR119 receptor and modulate its activity.

N-CYCLOPROPYL-N-PIPERIDINYL-AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF

The present invention relates to compounds of general formula I, wherein R1, LP, (Het)Ar1, (Het)Ar2 and n are as defined in the application, which have valuable pharmacological properties, and in particular bind