1544263-16-2

Upstream product

• 33577-99-0 2-ethynyl-benzoic acid methyl ester 
• 66-77-3 1-naphthaldehyde 
• 89525-53-1 1-bromo-2-benzylaminomethyl-4,5-dimethoxybenzene 

Downstream Products

• 1544262-73-8 (2-(3-(N-(2-bromo-4,5-dimethoxybenzyl)-N-benzylamino)-3-(naphthalen-1-yl)prop-1-ynyl)phenyl)methanol 
• 1544263-30-0 (E)-2-benzyl-4-(isobenzofuran-1(3H)-ylidene)-6,7-dimethoxy-3-(naphthalen-1-yl)-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Pd(0)-catalyzed regio- and stereoselective cyclization of alkynes: Selective synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4- tetrahydroisoquinolines and aze/oxepinoindoles

Palladium-catalyzed highly regio- and stereoselective 6-exo-dig and 7-endo-dig cyclization of functionalized propargylic compounds has been developed for the synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4- tetrahydroisoquinolines and aze/oxepinoindoles.