15446-51-2

Upstream product

• 99-76-3 methyl 4-hydroxylbenzoate 
• 604-68-2 α-D-glucopyranose peracetylate 
• 99-96-7 4-hydroxy-benzoic acid 
• 138949-72-1 cyanodelphin 

Downstream Products

• 492-61-5 β-D-glucose 
• 99-96-7 4-hydroxy-benzoic acid 
• 50-99-7 D-glucose 
• 75705-24-7 benzoic acid p-(β-D-glucopyranosyloxy)-methyl ester 
• 76306-75-7 2,3,4,6-O-tetraacetyl-4-β-D-glucopyranosyloxybenzoic acid 

Relevant academic research and scientific papers

STRUCTURE OF CYANODELPHIN, A TETRA-p-HYDROXYBENZOATED ANTHOCYANIN FROM BLUE FLOWER OF DELPHINIUM HYBRIDUM

Structure of cyanodelphin from blue petals of Delphinium hybridum was determined.It contains delphinidin nucleus, four molecules of p-hydroxybenzoic acid and seven molecules of hexoses.

Skin aging inhibitor

PROBLEM TO BE SOLVED: To provide a skin aging inhibitor. SOLUTION: A skin aging inhibitor contains, as an active ingredient, at least one compound selected from a hydroxy benzoic acid represented by formula (1) and a derivative thereof [in the formula R1 is hydrogen, a methyl group or a glucosyl group; in the formula R2 is a group selected from the group consisting of hydrogen, a C1-8 linear or branched hydrocarbon group, an aromatic hydrocarbon group, and a sugar residue of glucose or sorbitol] and a salt thereof. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

GLUCOSYLATION OF ISOMERIC HYDROXYBENZOIC ACIDS BY CELL SUSPENSION CULTURES OF MALLOTUS JAPONICUS

Cultured cells of Mallotus japonicus converted exogenous o-hydroxybenzoic acid into its O-glucoside after a lag period of 8 hr during which time the aglycone was taken up rapidly by the cells, partly excreted and then re-absorbed.The glucosylation of the aglycone into o-O-β-D-glucosylbenzoic acid began almost simultaneously with the induction of glucosyltransferase activity, and ca 78percent of the aglycone administered was transformed into the glucoside in 12 hr.On the other hand, m- and p-hydroxybenzoic acids were glucosylated immediately after administration, the latter yielding both its O-glucoside and glucose ester.Inhibitor experiments suggested the possible participation of either 70S or 80S ribosomes in the glucosylation of isomeric hydroxybenzoic acids.

UDP GLUCOSE: 4-(Β-D-GLUCOPYRANOSYLOXY)BENZOIC ACID GLUCOSYLTRANSFERASE FROM THE POLLEN OF PINUS DENSIFLORA

Exogenously supplied 4-hydroxybenzoic acid (HBA) was converted quantitatively to 4-(β-D- glucopyranosyloxy)benzoic acid (HBA glucoside) during 30 hr of germination of the pollen of Pinus densiflora (pine pollen). HBA(-HBA) was also converted to -HBA glucoside by pine pollen.UDP glucose: 4-(β-D-glucopyranosyloxy)benzoic acid glucosyltransferase from pine pollen was assayed by measuring the rate of formation of -HBA glucoside from -HBA and UDPG.The enzyme was partially purified from the pine pollen for the first.The Mr, of the enzyme was estimated to be ca 33 000 by Sephacryl S-300 gel filtration.The enzyme had a pH optimum at 7.5, and its activity was increased ca 50 and 60percent by the addition of 3 mM Ca(2+) and 0.1 mM EDTA, respectively.The Km values for UDP glucose and 4-hydroxybenzoic acid were 2.4 x 1E-4 M and 2.9 x 1E-3 M, respectively.Key Word Index - Pinus densiflora; Pinaceae; Japanese red pine; pollen germination; pollen tube elongation; 4-hydroxybenzoic acid; 4-(β-D-glucopyranosyloxy)benzoic acid; UDPG; 4-(β-D-glucopyranosyloxy)benzoic acid glucosyltransferase

GLUCOSYLATION OF PHENOLIC COMPOUNDS BY PLANT CELL CULTURES

Key Word Index-Glucosylation; biotransformation; plant cell culture; simple phenol;coumarin; flavonoid; anthraquinone.Ten culture strains derived from seven species of plants were examined for their ability to glucosylate exogenous phenolic compounds including four simple phenols, four coumarins, three flavonoids and three anthraquuinones.Suspension cultures of Datura, Lithospermum, Perilla and Catharanthus were capable of glucosylating m-hydroxybenzoic acid, umbelliferone, esculetin, daphnetin and liquiritigenin.In particular, Datura cultures glucosylated ca 90percent of umbelliferon within 24 hr after administration.Only Perilla cultures were capable of gucosylating rhein and emodin.The ability of glucosylating isomeric hydroxybenzoic acids varied widely with culture strains.A culture strain of Mallotus transformed p-hydroxybenzoic acid to p-O-β-D-glucosylbenzoic acid and p-hydroxybenzoic acid glucose ester, whereas only o-O-β-D-glucosylbenzoic acid was formed from o-hydroxybenzoic acid.