154460-33-0

Basic information

• Product Name: Cyclopentanecarboxylic acid, 2-amino-, methyl ester, (1R-cis)- (9CI)
• Synonyms: Cyclopentanecarboxylic acid, 2-amino-, methyl ester, (1R-cis)- (9CI);(1S,2R)-Methyl 2-aMinocyclopentanecarboxylate;Methyl (1R,2S)-2-aMinocyclopentanecarboxylate;(1R,2S)-2-Aminocyclopentanecarboxylic acid methyl ester
• CAS NO: 154460-33-0
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.18362
• Product Categories: CARBOXYLICESTER;AMINOACID
• Mol File: 154460-33-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 193.0±33.0 °C(Predicted)
• Appearance: /
• Density: 1.069±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 10.05±0.40(Predicted)
• CAS DataBase Reference: Cyclopentanecarboxylic acid, 2-amino-, methyl ester, (1R-cis)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 2-amino-, methyl ester, (1R-cis)- (9CI)(154460-33-0)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 2-amino-, methyl ester, (1R-cis)- (9CI)(154460-33-0)

Safety Data

• Hazardous Substances Data: 154460-33-0(Hazardous Substances Data)

Usage

General Description

Cyclopentanecarboxylic acid, 2-amino-, methyl ester, (1R-cis)- (9CI) is a chemical compound with the molecular formula C7H11NO2. It is commonly known as cis-2-aminocyclopentanecarboxylic acid methyl ester and is a derivative of cyclopentanecarboxylic acid. This chemical is a chiral compound with a specific configuration referred to as 1R-cis. It may be used in organic synthesis and chemical research as a building block or reagent. The compound's specific properties and potential applications would depend on its stereochemistry and relationship to other compounds in a given context.

Upstream product

• 128110-37-2 (1R,2S)-2-Amino-cyclopentane-1-carboxylic acid hydrochloride 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 67-56-1 methanol 
• 122672-46-2 (-)-cispentacin 
• 1033756-37-4 methyl (1R,2S)-2-{[(benzyloxy)carbonyl]amino}cyclopentanecarboxylate 

Downstream Products

• 1033881-19-4 (1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclopentanecarboxylate 
• 1033756-03-4 (1R,2S)-2-(4-fluoro-benzylamino)-cyclopentanecarboxylic acid methyl ester 

Relevant articles and documents

HCV PROTEASE INHIBITORS AND USES THEREOF

This invention relates to: (a) compounds of formula I and salts thereof that, inter alia, are useful as hepatitis C virus (HCV) inhibitors; (b) intermediates useful for the preparation of such compounds and salts; (c) pharmaceutical compositions comprising such compounds and salts; and (d) methods of use of such compounds, salts, and compositions.

5,6-Dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase

5,6-Dihydro-1H-pyridin-2-one analogs were discovered as a novel class of inhibitors of genotype 1 HCV NS5B polymerase. Among these, compound 4ad displayed potent inhibitory activities in biochemical and replicon assays (IC50 (1b) 10 nM; ICsu