154476-70-7

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 119649-27-3 4-((4-methoxybenzyl)oxy)butanal 
• 824-94-2 p-methoxybenzyl chloride 
• 119649-45-5 4-(p-methoxybenzyloxy)butan-1-ol 
• 27063-62-3 2-(4-methoxy-phenyl)-[1,3]dioxepane 
• 2746-25-0 p-Methoxybenzyl bromide 
• 3536-96-7 vinylmagnesium chloride 

Downstream Products

• 119649-29-5 1-(4-Benzyloxy-hex-5-enyloxymethyl)-4-methoxy-benzene 
• 442156-77-6 4-(tert-butyldiphenylsilanyloxy)-1-(4-methoxybenzyloxy)-5-hexene 
• 1586033-64-8 (S,Z)-1-((4S,5S)-5-((R)-1-(tert-butyldiphenylsilyloxy)octyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-6-(4-methoxybenzyloxy)hex-1-en-3-ol 
• 1586033-54-6 tert-butyl((R)-1-((4S,5S)-5-((S,E)-6-(4-methoxybenzyloxy)-3-(methoxymethoxy)hex-1-enyl)-2,2-dimethyl-1,3-dioxolan-4-yl)octyloxy)diphenylsilane 
• 1586033-62-6 tert-butyl-((R)-1-((4S,5S)-5-((S,Z)-6-(4-methoxybenzyloxy)-3-(methoxymethoxy)hex-1-enyl)-2,2-dimethyl-1,3-dioxolan-4-yl)octyloxy)diphenylsilane 
• 1571059-44-3 (S)-6-(4-methoxybenzyloxy)hex-1-en-3-ol 
• 1586033-46-6 (S)-1-methoxy-4-((4-(methoxymethoxy)hex-5-enyloxy)methyl)benzene 
• 1586033-53-5 (S,E)-1-((4S,5S)-5-((R)-1-(tert-butyldiphenylsilyloxy)octyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-6-(4-methoxybenzyloxy)hex-1-en-3-ol 
• 1586033-45-5 (S)-6-(4-methoxybenzyloxy)hex-1-en-3-yl acetate 
• 1017236-52-0 C₂₀H₃₄O₃Si 

Relevant academic research and scientific papers

Lewis acid catalyzed synthesis of cyclic carbonates, precursors of 1,2- and 1,3-diols

An eco-friendly synthesis of cyclic carbonates through a Lewis acid catalyzed cyclization of tert-butyl carbonates is described. These cyclic carbonates are precursors of 1,2- and 1,3-diols, and the developed method was applied to a short synthesis of a diarylheptanoid, (3S,5S)-alpinikatin.

Asymmetric synthesis of naturally occurring nonenolide xyolide through cross metathesis and macrolactonization reaction

Asymmetric total synthesis of xyolide, a small ring macrolide is presented in this article. The synthesis is achieved through an 'E' selective cross metathesis (CM) reaction between two appropriate fragments followed by lactonization by Shiina method. One of the fragments containing 7S,8S,9R stereocenters of xyolide is accessed from n-nonanal by adopting an organocatalytic asymmetric α-aminooxylation, Z-selective Ando olefination, and substrate directed dihydroxylation reaction. The other fragments containing 4S stereocenter was prepared by ME-DKR (metal enzyme combined dynamic kinetic resolution) method.

Stereoselective construction of quaternary chiral centers using Ti(III)-mediated opening of 2,3-epoxy alcohols: Studies directed toward the synthesis of penifulvins

A trisubstituted α,β-unsaturated ester moiety was suitably placed in a molecule also bearing an epoxy alcohol moiety at its other end to intramolecularly trap the intermediate radical, which was formed when the molecule was treated with Cp2Ti(I

Potent antimalarial febrifugine analogues against the Plasmodium malaria parasite

Although febrifugine (1) and isofebrifugine (2), alkaloids isolated from roots of the Dichroa febrifuga plant, show powerful antimalarial activity against Plasmodium falciparum, strong side effects such as the emetic effect have precluded their clinical u

Stereoselective synthesis of the 2,6-disubstituted tetrahydropyran-3-ol of the potent antitumor agent mucocin via an acyl radical cyclization

The intramolecular acyl radical cyclization of the acyl selenide 8, using a Z-vinylogous sulfonate to control rotamer population, affords the cis-2,6-disubstituted tetrahydropyran-4-one 9, applicable to the potent antitumor agent mucocin 1 in 81% yield.