154493-59-1

Basic information

• Product Name: 4-(4-Cyanophenyl)benzyl alcohol
• Synonyms: 4-(4-Cyanophenyl)benzyl alcohol;4-[4-(hydroxymethyl)phenyl]benzonitrile
• CAS NO: 154493-59-1
• Molecular Formula: C₁₄H₁₁NO
• Molecular Weight: 209.24
• Mol File: 154493-59-1.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-Cyanophenyl)benzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Cyanophenyl)benzyl alcohol(154493-59-1)
• EPA Substance Registry System: 4-(4-Cyanophenyl)benzyl alcohol(154493-59-1)

Safety Data

• Hazardous Substances Data: 154493-59-1(Hazardous Substances Data)

Upstream product

• 623-00-7 4-bromobenzenecarbonitrile 
• 87199-17-5 4-formylphenylboronic acid, 
• 873-76-7 para-Chlorobenzyl alcohol 
• 126747-14-6 4-cyanophenylboronic acid 
• 59016-93-2 p-hydroxymethylphenylboronic acid 
• 50670-55-8 4-(4-cyanophenyl)-benzaldehyde 

Downstream Products

• 50670-51-4 4-(bromomethyl)-4'-cyanobiphenyl 

Relevant articles and documents

Copper-Free Click Reaction Sequence: A Chemoselective Layer-by-Layer Approach

An additive-free chemoselective ligation of dual clickable building blocks is demonstrated. The challenge of balancing reactivity and stability was achieved by employing a small, electron-deficient tetrazine bearing an azido group and an enol ether functionalized cyclooctyne. The chemoselective sequence of strain-promoted azide-alkyne cycloaddition (SPAAC) and inverse-electron-demand Diels-Alder (IEDDA) reaction is demonstrated with a cholic acid derived triazide as a molecular surface model for layer-by-layer synthesis.

PdO hydrate as an efficient and recyclable catalyst for the Suzuki-Miyaura reaction in water/ethanol at room temperature

PdO?1.4H2O 1 prepared in our laboratories, as well as commercially available palladium oxides 2-4 have been found to act as efficient catalysts for the Suzuki-Miyaura reaction in ethanol/water mixture at room temperature in air. Thus, in the presence of 1 mol% catalyst, the reaction between different aryl bromides and arylboronic acids afforded a wide range of functionalized biphenyls in quantitative yield. Catalyst 1 has shown to be the most active for all couples of substrates, and it can be recovered and recycled several times without marked loss of activity. It has been demonstrated by means of suitable tests that the true catalyst is a soluble form of palladium originated by metal leaching from the metal oxide precursor. It is worth of note that the amount of catalyst both in the solution and in the isolated organic product is about 1 ppm.

Peptide nanofibers decorated with Pd nanoparticles to enhance the catalytic activity for C-C coupling reactions in aerobic conditions

We report the synergistic effects of peptide nanofibers decorated with Pd nanoparticles to enhance the catalytic activity for C-C coupling reactions in mild and aerobic conditions.