154497-83-3Relevant academic research and scientific papers
Synthesis of novel substituted pyridines as inhibitors of endothelin converting enzyme-1 (ECE-1)
Massa, Mark A.,Patt, William C.,Ahn, Kyunghye,Sisneros, Andre M.,Herman, Sarah B.,Doherty, Annette
, p. 2117 - 2122 (2007/10/03)
A series of bi-aryl pyridine carboxylic acids has been prepared and evaluated as inhibitors of ECE-1. The analogs were prepared by Pd catalyzed cross couplings of halogenated pyridines with heteroaryl organo -boranes, - tinate or -zincate derivatives.
PYRIDINE COMPOUNDS WHICH ARE USEFUL AS LEUKOTRIENE-B4-ANTAGONISTS
-
, (2008/06/13)
The invention relates to new pyridine derivatives of general formula I which have useful properties, e.g., as leukotriene-B 4-antagonists. Pharmaceutical compositions containing these compounds can be used to treat various diseases.
