15450-66-5

Basic information

• Product Name: N-[(E)-(4-methoxyphenyl)methylidene]-4-nitroaniline
• Synonyms: 4-(4-Methoxybenzylideneamino)nitrobenzene; Aniline, N- (p-methoxybenzylidene)-p-nitro-; Aniline, N-(p-methoxybenzylidene)-p-nitro-; Benzenamine, N-((4-methoxyphenyl)methylene)-4-nitro-; N-(p-Methoxybenzylidene)-p-nitroaniline
• CAS NO: 15450-66-5
• Molecular Formula: C₁₄H₁₂N₂O₃
• Molecular Weight: 256.2567
• Mol File: 15450-66-5.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 432.1°C at 760 mmHg
• Flash Point: 215.1°C
• Density: 1.18g/cm³
• Vapor Pressure: 2.87E-07mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: N-[(E)-(4-methoxyphenyl)methylidene]-4-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(E)-(4-methoxyphenyl)methylidene]-4-nitroaniline(15450-66-5)
• EPA Substance Registry System: N-[(E)-(4-methoxyphenyl)methylidene]-4-nitroaniline(15450-66-5)

Safety Data

• Hazardous Substances Data: 15450-66-5(Hazardous Substances Data)

Upstream product

• 100-01-6 4-nitro-aniline 
• 105-13-5 4-Methoxybenzyl alcohol 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 41226-85-1 2-(4-chloro-phenyl)-4-(4-methoxy-phenyl)-3-(4-nitro-phenyl)-oxazolidine-5,5-dicarbonitrile 
• 111969-92-7 1-(p-nitrophenyl)-3-(3',4'-dichlorophenoxy)-4-(p-methoxyphenyl)-azetidin-2-one 
• 74650-14-9 2-(4-Methoxy-phenyl)-1-(4-nitro-phenyl)-aziridine 
• 19348-90-4 diphenyl 1-(4-nitrophenylamino)-1-(4-methoxyphenyl)methanephosphonate 
• 111536-91-5 3-phenyl-5-(p-methoxyphenyl)-4-(p-nitrophenyl)-4,5-dihydro-1,2,4-oxadiazol 
• 111969-93-8 1-(p-nitrophenyl)-3-phenoxy-4-(p-methoxyphenyl)-azetidin-2-one 
• 76553-77-0 [1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-(4-nitro-phenyl)-amine; compound with trichloro-acetic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 3646-57-9 bis(4-nitrophenyl)diazene 
• 1639463-76-5 C₁₅H₁₂BrN₃O₃ 
• 1639463-83-4 4-(4-methoxyphenyl)-3-(4-nitrophenyl)-1,3-oxazetidin-2-one 
• 1146114-33-1 2-(4-methoxyphenyl)-1-(4-nitrophenyl)-2,3-dihydropyridin-4(1H)-one 

Relevant articles and documents

Triarylmethyl Cation-Catalyzed Three-Component Coupling for the Synthesis of Unsymmetrical Bisindolylmethanes

An efficient synthesis of unsymmetrical bisindolylmethanes has been accomplished using triarylmethyl cations to catalyze the reaction of N-arylimines with two different indoles. Optimization of the organocatalyst by tuning cation stability allows for excellent single addition selectivity when coupled with p-nitrophenyl imines. The optimal catalyst is commercially available, and the reaction minimizes waste and environmental impact by employing a one-to-one ratio of starting materials. The intermediates can be isolated or used in situ in a one-pot two-step reaction to generate unsymmetrical bisindolylmethanes in high yields. The reaction tolerates a broad range of imines with the highest yields observed for electron-poor and neutral imines. A wide range of indole nucleophiles are also successfully employed allowing for the creation of a large variety of unsymmetrical bisindolylmethanes.

Dual Heterogeneous Catalyst Pd-Au@Mn(II)-MOF for One-Pot Tandem Synthesis of Imines from Alcohols and Amines

A new Mn(II) metal-organic framework (MOF) 1 was synthesized by the combination of 4,4,4-trifluoro-1-(4-(pyridin-4-yl)phenyl)butane-1,3-dione (L) and Mn(OAc)2 in solution. 1 features a threefold-interpenetrating NbO net containing honeycomb-like channels, in which the opposite Mn(II)···Mn(II) distance is 23.5075(10) ?. Furthermore, 1 can be an ideal platform to support Pd-Au bimetallic alloy nanoparticles to generate a composite catalytic system of Pd-Au@Mn(II)-MOF (2). 2 can be a highly active bifunctional heterogeneous catalyst for the one-pot tandem synthesis of imines from benzyl alcohols and anilines and from benzyl alcohols and benzylamines.

One pot photoredox decarboxylation reaction of N-cyano(α-bromo- α-phenyl)methylanilines leading to synthesis of four-membered cyclic carbamates

A new four-membered cyclic carbamates have been synthesized through solar irradiation of N-cyano(α-bromo-α-phenyl)methylanilines in their aqueous methanolic solution using iodide salt in basic medium. These compounds have been characterized as 3,4-diphenyl-1,3oxazetidin-2-one through their elemental analysis, IR, 1H-NMR, 13C-NMR, and mass spectral studies.