15450-93-8

Usage

Chemical compound

1H-Phosphole, 2,5-dihydro-3-methyl-1-phenyl-

Structure

Contains a phosphole ring and a phenyl group attached

Composition

Contains phosphorus, carbon, and hydrogen atoms

Properties

Heterocyclic compound with interesting properties

Applications

Potential use in organic synthesis and as an intermediate in chemical production

Target for research

Unique structure and reactivity make it an interesting target for further exploration in phosphorus chemistry

Upstream product

• 644-97-3 Dichlorophenylphosphine 
• 78-79-5 isoprene 
• 7564-51-4 2,5-dihydro-3-methyl-1-phenyl-1H-phosphole 1-oxide 
• 17786-50-4 1-bromo-3-methyl-1-phenyl-2,5-dihydro-1H-phospholium; bromide 
• 39834-66-7 1-bromo-3-methyl-3-phospholene 

Downstream Products

• 15450-94-9 1-benzyl-3-methyl-1-phenyl-2,5-dihydro-1H-phospholium; bromide 
• 143924-62-3 cis-4,5-dimethyl-1,2-diphenyl-1,2,3,6-tetrahydro-1,2-diphosphinine 
• 143924-62-3 trans-4,5-dimethyl-1,2-diphenyl-1,2-diphosphacyclohex-4-ene 
• 14409-95-1 1-phenyl-3,4-dimethyl-2,5-dihydro-1H-phosphole 
• 2290-06-4 phenylphosphinidene 
• 2176-06-9 diphenyldiphosphene 
• 78-79-5 isoprene 
• 14463-05-9 1,2-Diphenyl-4,5-dimethyl-tetrahydro-1,2-diphosphinin 
• 179989-97-0 1-phenyl-2,5-dihydro-3-methyl-1H-phosphole-1-borane 
• 832-01-9 methyl p-methoxycinnamate 
• 103-26-4 methyl cinnamate 
• 637-57-0 methyl 4-nitrocinnamate 

Relevant academic research and scientific papers

Isomerization and application of phospholene oxides

In this research, an investigation of the isomerization and the applications of 3-phospholene oxides were elaborated. The isomerization of 3-phospholene oxides to 2-phospholene oxides was investigated under thermal condition. The application of bases and acids was also tested in this reaction. Moreover, the isomerization was also elaborated via the formation of halophosphonium salt intermediates. The 3-phospholene oxides were deoxygenated and transformed to the corresponding palladium complexes.

A study on the deoxygenation of trialkyl-, dialkyl-phenyl- and alkyl-diphenyl phosphine oxides by hydrosilanes

The deoxygenation of 1-alkyl-3-methyl-3-phospholene 1-oxides, which may be regarded as trialkyl phosphine oxides (R3PO), and the reduction of dialkyl-phenylphosphine oxides (R2PhPO) and methyl-diphenylphosphine oxide (MePh2PO) have been elaborated by applying user-friendly silanes, such as tetramethyldisiloxane (>SiH–O–HSin) under solvent-free, catalyst-free, and microwave (MW)-assisted conditions. New silanes of type Ar2SiH2, alkyl2SiH2, and Ar3SiH were also applied in a few cases. The reactivity of the phosphine oxides and the silanes could be mapped on the basis of our experimental data.

A new family of platinum(ii) complexes incorporating five-and six-membered cyclic phosphine ligands

New platinum complexes of the type cis-Pt(L)2Cl2 have been synthesized from five-and six-membered cyclic phosphines, which were prepared after deoxygenating a series of phosphine oxides (3-phospholene oxides, phospholane oxides, a 1,

Generation and utilisation of P-cyclic α-methoxycarbonyl- methylenephosphoranes

Phosphonium salts 3 obtained by the quaternisation of 1-aryl-2,5-dihydro- 1H-phospholes 2 with methyl bromoacetate are suitable precursors of the corresponding heterocyclic phosphoranes 5. They were generated in situ using DBU at ambient temperature. The phosphoranes (5) were used in Wittig reaction with benzaldehydes and in acylation with methyl (chloroformyl)formate to afford in the latter case, heterocyclic α,β-bis(methoxycarbonyl)-β- oxophosphoranes (7).

General Approaches to Phosphinidenes via Retroadditions

The retroaddition strategy for the generation of phosphinidenes involves thermal and photochemical decomposition of 1-arylphosphiranes and photolysis of 1-aryl-3-phospholenes.Evidence that free phosphinidenes are produced as reactive intermediates includes a lack of dependence of the conversion rate on precursor and substrate concentrations and the nature of the reaction products.These are best rationalized by the addition of phosphinidenes to carbon-carbon ?-bonds forming three-membered rings and the dimerization of phosphinidenes to diphosphenes.

Asymmetrical hydrogenation by means of optically active aluminum hydride derivatives

A prochiral or racemic substrate such as a prochiral ketone is converted into an optically active product through a process wherein said substrate is subjected to an asymmetric hydrogen transfer reaction by means of an optically active amino-alane or polyimino-alane represented by the formula wherein R, R1 and R2 are alkyl, aryl or cycloalkyl radicals, n is an integer higher than 4, and which contains an Al -- N direct bond and an Al -- H bond per aluminum atom, and the third substituent bound to aluminum is halogen, --H, STR1 or --OR wherein R has the aforesaid meaning, and wherein the asymmetry center is constituted by a primary or secondary amine group containing an optically active alkyl radical.