154501-23-2

Upstream product

• 154501-21-0 25,27-bis(4-(4-benzyloxyphenyl)butoxy)-26,28-dihydroxy-p-tert-butylcalix<4>arene 
• 73227-34-6 5,11,17,23-tetra-tertbutyl 25,26,27,28-tetra-hydroxycalix{4}arene*C7H8 
• 130783-40-3 1-benzyloxy-4-(4-hydroxybutyl)benzene 
• 154501-19-6 4-(4-benzyloxyphenyl)butyl tosylate 
• 6686-26-6 4-(4-benzyloxyphenyl)butyric acid 
• 7021-11-6 4-(4-hydroxyphenyl)butanoic acid 
• 157432-87-6 5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene 
• 154501-20-9 25,27-bis(3-(4-benzyloxyphenyl)propoxy)-26,28-dihydroxy-p-tert-butylcalix<4>arene 

Relevant academic research and scientific papers

Head-to-Tail Connected Double Calix[4]arenes

New macrotricyclic compounds consisting of two calix[4]arene substructures connected by aliphatic chains of various length (three to five carbon atoms) between two opposite p-positions and two distal phenolic oxygens have been synthesized. Starting with p-tert-butyl-calix[4]arene, two O-protected phenolic units are attached via ether links in 1,3-position by reaction with the corresponding tosylates. After deprotection, the new calix[4]arene is formed by fragment condensation with 2,6-tobromomethylated 4-alkylphenols. The structure of one example (8c) has been confirmed by single crystal X-ray analysis. Both calixarene parts assume the cone conformation, a molecule of acetonitrile being included in both cavities.