154548-01-3Relevant academic research and scientific papers
Asymmetric Synthesis of 1,1-Disubstituted Tetralins and Dihydronaphthalenes by Diastereoselective Addition of Lithiosilanes to Chiral Naphthalenes
Hulme, Alison N.,Meyers, A. I.
, p. 952 - 953 (1994)
Highly diastereoselective additions of lithiosilanes to chiral naphthalenes can be performed in ether/THF.Trapping of the resulting azaenolate, followed by protodesilylation, allows access to 1,1-disubstituted tetralins or dihydronaphthalenes in good yields and high enantiomeric excess.
