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2-(3-NITRO-PHENYL)-1H-BENZOIMIDAZOLE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

15456-62-9

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15456-62-9 Usage

Structure

Benzimidazole derivative with a nitrophenyl group attached at the 2-position

Potential applications

Medicinal chemistry and drug development

Pharmacological properties

Anti-inflammatory, anti-cancer, and anti-microbial activities

Investigation for treatment

Various diseases and disorders

Interest in pharmaceutical industry

High due to diverse pharmacological properties and potential therapeutic applications

Further studies needed

To fully understand the biological activities and potential therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 15456-62-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,5 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 15456-62:
(7*1)+(6*5)+(5*4)+(4*5)+(3*6)+(2*6)+(1*2)=109
109 % 10 = 9
So 15456-62-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H9N3O2/c17-16(18)10-5-3-4-9(8-10)13-14-11-6-1-2-7-12(11)15-13/h1-8H,(H,14,15)

15456-62-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(3-nitrophenyl)-1H-benzimidazole

1.2 Other means of identification

Product number -
Other names 2-(3-NITROPHENYL)-1H-BENZOIMIDAZOLE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15456-62-9 SDS

15456-62-9Relevant academic research and scientific papers

Synthesis of novel benzimidazoles at room temperature, under solvent-free condition and their biological studies

Gulati, Susheel,Singh, Rajvir,Sangwan, Suman,Rana, Suprita

, p. 167 - 179 (2021)

Abstract: An efficient and facile synthesis of substituted novel benzimidazoles (3a–3h) mediated by fruit juices viz. Cocos nucifera L. juice, Citrus limetta juice and Citrus sinensis L. juice, via condensation of substituted aldehydes (1a–1h) and o-pheny

Synthesis of 2-substituted benzimidazoles using 25 % Co/Ce-ZrO2 as a heterogeneous and nanocatalyst

Behbahani, Farahnaz K.,Rezaee, Elham,Fakhroueian, Zahra

, p. 2184 - 2190 (2014)

25 % Co/Ce-ZrO2 nano fine particles are reported as a new catalyst for the efficient synthesis of 2-arylbenzimidazoles. A simple and convenient procedure, reusable catalyst, easy purification and shorter reaction times are the advantageous features of this method. Also prepared catalyst according to the coprecipitation method was characterized by common techniques such as SEM, XRD, FTIR and so on analysis. The catalyst is reusable and, reusable catalyst was characterized by XRD and FTIR techniques. Graphical Abstract: [Figure not available: see fulltext.]

Application of sulfamic acid as an eco-friendly catalyst in an expedient synthesis of benzimidazoles

Chakrabarty, Manas,Karmakar, Sulakshana,Mukherji, Ajanta,Arima, Shiho,Harigaya, Yoshihiro

, p. 967 - 974 (2006)

Sulfamic acid, an eco-friendly and zwitterionic solid, proved to be a very efficient catalyst for the reaction of ortho-phenylenediamine with aryl aldehydes in ethanol at room temperature to furnish both 1-arylmethyl-2-aryl- and 2-arylbenzimidazoles in very good to excellent overall yields.

Amphiphilic Dendrimer as Reverse Micelle: Synthesis, Characterization and Application as Homogeneous Organocatalyst

Sherly mole,George, Smitha,Shebitha,Kannan,Mathew, Suseela,Asha,Sreekumar

, (2019)

The core and surface terminal groups are the two main catalytic sites in a dendrimer. In most of the reported examples, the catalytic sites in dendritic catalysis are the surface terminal functional groups. This perspective article concerned with the dend

Efficient preparation of acidic ionic liquid-functionalized reduced graphene oxide and its catalytic performance in synthesis of benzimidazole derivatives

Hanoon,Kowsari,Abdouss,Zandi,Ghasemi

, p. 1751 - 1766 (2017)

Abstract: This article reports an efficient method with a simple workup for the facile synthesis of benzimidazole derivatives using an acidic ionic liquid covalently supported on graphene sheets. The catalyst was efficiently synthesized and characterized

Effect of Cd-doping on the catalytic activity of ZnO nanoflakes in the synthesis of benzimidazoles

Kunde, Sachin P.,Kanade, Kaluram G.,Karale, Bhausaheb K.,Akolkar, Hemantkumar N.,Randhavane, Pratibha V.,Shinde, Santosh T.

, p. 7277 - 7290 (2017)

Abstract: A set of hierarchical CdxZn1?xO nanoflakes (x?=?0, 0.01 and 0.03) was prepared by the co-precipitation method using methanol as solvent. The prepared samples were characterized by UV–visible, X-ray diffraction, field emissi

[Diaquo{bis(p-hydroxybenzoato-κ1O1)}(1-methylimidazole- κ1N1)}copper(II)]: Synthesis, crystal structure, catalytic activity and DFT study

Brahman, Dhiraj,Chhetri, Sailesh,Kamath, Amarjit,McArdle, Patrick,Sinha, Biswajit

, (2021/09/04)

Metal-organic hybrid complexes often exhibit large surface area, pore volume, fascinating structures and potential applications including catalytic applications. Hence a new metal-organic hybrid complex [Diaquo{bis(p-hydroxybenzoato-κ1O1)}(1-methylimidazole- κ1N1)}copper(II)] was synthesized using conventional method. Physico-chemical characterization of the complex was performed with FTIR spectroscopy, single crystal X-ray diffraction, TGA, EPR and FESEM. Single crystal X-ray diffraction study suggests it to be three dimensional with space group P212121 (orthorhombic). The crystal achieves its three-dimensional structure and stability through extensive intermolecular hydrogen bonding. Hirshfeld surface analysis, catalytic activity and DFT study of the complex was also performed. The synthesized complex acts as good catalyst in benzimidazole synthesis with good recyclability as catalyst up to 5th run.

1-Methylimidazolium ionic liquid supported on Ni@zeolite-Y: fabrication and performance as a novel multi-functional nanocatalyst for one-pot synthesis of 2-aminothiazoles and 2-aryl benzimidazoles

Kalhor, Mehdi,Zarnegar, Zohre

, p. 519 - 540 (2021/12/03)

In the present study, 1-methyl-3-(3-trimethoxysilylpropyl)-1H-imidazol-3-ium chloride-supported Ni@zeolite-Y-based nanoporous materials (Ni@zeolite-Im-IL) were synthesized and their structures were confirmed using different characterization techniques such as FT-IR, FE-SEM, EDX, XRD, BET and TGA-DTG analyses. In order to synthesize this multi-functional nano-system, zeolite-NaY was modified first, with exchanged Ni2+ ions and 3-chloropropyltriethoxysilane (CPTES) as a coupling reagent and then functionalized to imidazolium chloride ionic liquid by N-methylimidazole. New multi-functional nano-material of Ni@zeolite-Im-IL demonstrated high activity in the catalytic synthesis of 2-aminothiazoles 3a–l by one-pot reaction of methylcarbonyls, thiourea and iodine at 80?°C in DMSO with good to excellent yields (85–98%). Also, the catalytic synthesis of 2-aryl benzimidazoles, 6a–m was performed by the condensational reaction of o-arylendiamine and aromatic aldehydes in EtOH at room temperature with excellent yields (90–98%). Advantages of this efficient synthetic strategy include higher purity and shorter reaction time, excellent yield, easy isolation of products, the good stability, activity and feasible reusability of the metallic ionic liquid nanocatalyst. These benefits have made this method more compatible with the principles of green chemistry. Graphical abstract: [Figure not available: see fulltext.]

Design, preparation, biological investigations and application of a benzoguanamine-based nickel complex for the synthesis of benzimidazoles

Habibi, Davood,Heydari, Somayyeh,Karamian, Roya,Oliaei, Sajjad,Ranjbar, Nika

, (2022/01/19)

The new magnetic-supported benzoguanamine-based nickel complex was prepared, characterized by various procedures and used as a capable heterogeneous nano-catalyst for the synthesis of diverse 2-phenyl-1H-benzo[d]imidazoles from the reaction o-phenylenedia

Al2O3/CuI/PANI nanocomposite catalyzed green synthesis of biologically active 2-substituted benzimidazole derivatives

Chandra, Ramesh,Hooda, Sunita,Kohli, Sahil,Rathee, Garima

, p. 7750 - 7758 (2021/06/16)

This work is generally focused on the synthesis of an efficient, reusable and novel heterogeneous Al2O3/CuI/PANI nanocatalyst, which has been well synthesized by a simple self-assembly approach where aniline is oxidized into PANI and

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