3459-99-2 Usage
Uses
Used in Organic Synthesis:
3-Nitro-benzenecarboximidamide is used as a building block in organic synthesis for the creation of a variety of complex organic molecules. Its unique structure allows for multiple synthetic pathways, making it a valuable component in the synthesis of specialty chemicals.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 3-Nitro-benzenecarboximidamide is utilized as a precursor in the synthesis of various drugs. Its functional groups can be modified to produce active pharmaceutical ingredients with specific therapeutic properties, contributing to the development of new medications.
Used in Agrochemical Production:
3-Nitro-benzenecarboximidamide also finds application in the agrochemical sector, where it is employed as a starting material for the synthesis of pesticides and other crop protection agents. Its reactivity and functional groups enable the production of effective compounds designed to protect crops from pests and diseases.
Safety Precautions:
Given its potentially explosive nature due to the nitro group, 3-nitro-benzenecarboximidamide must be handled with extreme care. Proper safety measures, including the use of protective equipment and adherence to specific storage and handling protocols, are essential to prevent accidents and ensure the safe use of 3-NITRO-BENZENECARBOXIMIDAMIDE in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 3459-99-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,5 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3459-99:
(6*3)+(5*4)+(4*5)+(3*9)+(2*9)+(1*9)=112
112 % 10 = 2
So 3459-99-2 is a valid CAS Registry Number.
3459-99-2Relevant articles and documents
Reaction of arylhalodiazirines with thiophenoxide: A redox process
Creary, Xavier,Sky, Anthony F.,Phillips, Gillian,Alonso, David E.
, p. 7584 - 7592 (2007/10/02)
Phenylbromodiazirine reacts with thiophenoxide ion in methanol to give benzonitrile, benzamidine, ammonia, and diphenyl disulfide. The reaction is general for arylhalodiazirines, with electron-withdrawing groups on the aromatic ring exerting a small rate-enhancing effect. Three potential mechanisms are suggested for this redox process. These mechanisms include an N-sulfenylated diazirine, a diazirinyl radical, and a diazirinyl anion. Ring opening of these intermediates and subsequent transformations would lead to benzonitriles, benzamidine, and ammonia. A key intermediate in these transformations is PhSNH2, 32. This intermediate has been independently generated and found to rapidly convert to ammonia and diphenyl disulfide under the reaction conditions. Another proposed intermediate, N-(phenylthio)benzamidine, 38, has also been independently generated and subjected to the reaction conditions, where benzamidine and more diphenyl disulfide result. Theoretical calculations suggest the existence of isomeric diazirinyl anions. In addition to a diazirinyl ion with charge essentially on carbon, there is also an allylic-type ion with charge on the two nitrogen atoms. Single-electron reduction of a diazirinyl radical necessarily leads to a nitrogen-centered diazirinyl anion. Conversion of this anion to the carbon-centered diazirinyl anion is a forbidden process. These theoretical studies suggest that the diazirinyl anion may be a viable intermediate in solution.
