154592-40-2

Basic information

• Product Name: 2H-Pyrrole, 3,4-dihydro-2-methyl-5-phenyl-
• CAS NO: 154592-40-2
• Molecular Formula: C11H13N
• Molecular Weight: 159.231
• Mol File: 154592-40-2.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 2H-Pyrrole, 3,4-dihydro-2-methyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyrrole, 3,4-dihydro-2-methyl-5-phenyl-(154592-40-2)
• EPA Substance Registry System: 2H-Pyrrole, 3,4-dihydro-2-methyl-5-phenyl-(154592-40-2)

Safety Data

• Hazardous Substances Data: 154592-40-2(Hazardous Substances Data)

Upstream product

• 1250849-38-7 (E)-1-phenylpent-4-en-1-one O-pivaloyloxime 
• 1250849-42-3 C₁₂H₁₅NO 
• 1250849-46-7 C₁₃H₁₇NO₂ 
• 1250849-48-9 C₁₈H₁₉NO 
• 187748-89-6 E-O-methyl 3-butenyl phenyl ketone oxime 
• 220446-51-5 (E)-5-phenyl-1-pentene-1-one O-pentafluorobenzoyloxime 
• 3042-21-5 2-methyl-5-phenyl-1H-pyrrole 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 3240-29-7 1-Phenylpent-4-en-1-one 
• 98-88-4 benzoyl chloride 
• 89968-81-0 1-Phenylpentane-1,4-diol 
• 111-27-3 hexan-1-ol 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 6919-61-5 N-methoxy-N-methylbenzamide 

Downstream Products

• 1357391-22-0 (2R,5R)-2-methyl-5-phenylpyrrolidine 
• 1357391-22-0 (2S,5S)-2-methyl-5-phenylpyrrolidine 
• 1309456-86-7 C₁₃H₁₂F₃NO 

Relevant articles and documents

Visible-light-promoted carboimination of unactivated alkenes for the synthesis of densely functionalized pyrroline derivatives

An efficient strategy which integrates visible-light-induced iminyl-radical formation with carboimination of unactivated alkenes has been developed for the easy access of densely functionalized pyrroline derivatives. With fac-[Ir(ppy)3] as photoredox catalyst, the acyl oximes were converted into iminyl radical intermediates by one electron reduction, and evolve through a cascade of intramolecular cyclization and intermolecular carbon radical trapping to give the functionalized pyrrolines. The utilization of silyl enol ethers as coupling partners not only allows the introduction of synthetically useful ketone functionalities but also renders catalyst regeneration without any external reductants. This protocol is characterized by its mild reaction conditions and the tolerance of a broad range of functionalities.

Method for synthesizing 2-methyl-5-phenyl-3,4-dihydro-2H-pyrrole compound

The invention discloses a method for synthesizing a 2-methyl-5-phenyl-3,4-dihydro-2H-pyrrole compound. the method comprises the following steps: adding gamma,delta-unsaturated oxime ether, samarium metal and iodine by one-pot method into a reaction contai

Visible-Light-Mediated Iminyl Radical Generation from Benzyl Oxime Ether: Synthesis of Pyrroline via Hydroimination Cyclization

The treatment of an O-(4-methoxybenzyl) oxime ether bearing an olefin substituent and 1-chloroanthraquinone (1-Cl-AQN) catalyst in 2-butanone under visible-light irradiation affords pyrroline via an iminyl radical intramolecular hydroimination. Mechanistic studies indicate that iminyl radical generation mainly proceeds by hydrogen abstraction of the photocatalyst from the benzyl position of the oxime. Moreover, the hydrogen atom was identified in circulation from the benzylic position of the substrates between AQN and 2-butanone to quench the carbon radical without requiring any additional reagents.