154616-13-4Relevant academic research and scientific papers
α-Carbonyl Radicals for Total Synthesis of Natural Products
Sha, Chin-Kang,Jean, Tsong-Shin,Yau, Nei-Tung,Huang, Shih-Jung,Chiou, Ruey-Torn,et al.
, p. 637 - 640 (2007/10/02)
Intramolecular cyclization of α-carbonyl radicals to the trimethylsilylacetylenic side chain gives bicyclic vinylsilane ketones and enones.Application of the cyclization to total synthesis of (+/-)-modhephene is described.
Intramolecular cyclization reactions of enone radicals
Sha,Shen,Jean,Chiu,Tseng
, p. 7641 - 7644 (2007/10/02)
Enone radicals, generated from the corresponding iodo enones, or vinylogous esters and amides, undergo intramolecular cyclization to the tethered trimethylsilyl acetylenic side chain to give the carbo- or heterobicyclic enones.
