154639-24-4 Usage
Description
RK-682, also known as TAN 1364B, is a protein tyrosine phosphatase (PTP) inhibitor and the racemic and monomeric form of a tetronic acid complex isolated from Streptomyces species. It was first patented by Takeda in 1993 and later identified by Ciba Geigy as the sodium salt of 3-hexadecanoyl-5-hydroxymethyltetronic acid. RK-682 inhibits the activity of various PTPs and has been shown to form aggregates in solution, binding to both the PTP binding site and protein surfaces.
Uses
Used in Pharmaceutical Applications:
RK-682 is used as a PTP inhibitor for its ability to inhibit the activity of PTPs such as LMW-PTP, CDC25B, and PTP1B. This makes it a potential candidate for the development of drugs targeting various diseases and conditions related to the dysregulation of PTP activity.
Used in Research Applications:
RK-682 is used as a research tool for studying the role of protein tyrosine phosphatases in cellular processes and signaling pathways. Its ability to inhibit specific PTPs makes it a valuable compound for understanding the molecular mechanisms underlying various biological functions and diseases.
Used in HIV-1 Protease Inhibition:
RK-682 is used as an inhibitor of HIV-1 protease, which plays a crucial role in the replication of the virus. By inhibiting this enzyme, RK-682 may help in the development of antiretroviral drugs to combat HIV infection.
Used in Enzyme Inhibition Studies:
RK-682 is used as an inhibitor of various enzymes, including phospholipase A2 and heparinase. Its ability to inhibit these enzymes makes it a useful compound for studying the roles of these enzymes in various biological processes and for the development of drugs targeting these enzymes.
Check Digit Verification of cas no
The CAS Registry Mumber 154639-24-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,6,3 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 154639-24:
(8*1)+(7*5)+(6*4)+(5*6)+(4*3)+(3*9)+(2*2)+(1*4)=144
144 % 10 = 4
So 154639-24-4 is a valid CAS Registry Number.
